ECsens, CITIC-UGR, Department of Electronics and Computer Technology, University of Granada, Granada, Spain.
Unit of Excellence in Chemistry Applied to Biomedicine and the Environment of the University of Granada, Granada, Spain.
Nat Commun. 2022 Jan 10;13(1):72. doi: 10.1038/s41467-021-27733-3.
The use of facemasks by the general population is recommended worldwide to prevent the spread of SARS-CoV-2. Despite the evidence in favour of facemasks to reduce community transmission, there is also agreement on the potential adverse effects of their prolonged usage, mainly caused by CO rebreathing. Herein we report the development of a sensing platform for gaseous CO real-time determination inside FFP2 facemasks. The system consists of an opto-chemical sensor combined with a flexible, battery-less, near-field-enabled tag with resolution and limit of detection of 103 and 140 ppm respectively, and sensor lifetime of 8 h, which is comparable with recommended FFP2 facemask usage times. We include a custom smartphone application for wireless powering, data processing, alert management, results displaying and sharing. Through performance tests during daily activity and exercise monitoring, we demonstrate its utility for non-invasive, wearable health assessment and its potential applicability for preclinical research and diagnostics.
全球范围内建议普通人群使用口罩来预防 SARS-CoV-2 的传播。尽管有证据表明口罩可以减少社区传播，但也同意其长时间使用可能产生的不利影响，主要是由于 CO 再呼吸引起的。在此，我们报告了一种用于实时测定 FFP2 口罩内气态 CO 的传感平台的开发。该系统由光电化学传感器与灵活的、无电池的、近场启用标签组成，分辨率和检测限分别为 103 和 140ppm，传感器寿命为 8 小时，与推荐的 FFP2 口罩使用时间相当。我们包括一个定制的智能手机应用程序，用于无线供电、数据处理、警报管理、结果显示和共享。通过日常活动和运动监测中的性能测试，我们证明了它在非侵入性、可穿戴健康评估中的实用性，以及在临床前研究和诊断中的潜在适用性。
