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髋部骨折住院的八旬患者谵妄的预测因素

Predictors of Delirium in Octogenarian Patients Hospitalized for a Hip Fracture.

作者信息

Plaza-Carmona María, Requena-Hernández Carmen, Jiménez-Mola Sonia

机构信息

Geriatrics Unit, León University Hospital, 24008 León, Spain.

Department of Psychology, Sociology and Philosophy, University of León, 24071 Leon, Spain.

出版信息

Int J Environ Res Public Health. 2020 Oct 14;17(20):7467. doi: 10.3390/ijerph17207467.

Abstract

INTRODUCTION

Since delirium is a major complication that can arise after a patient with a hip fracture has been hospitalized, it is considered to be one of the most common geriatric conditions. Therefore, its prevention and early detection are essential for reducing both the length of the patient's stay in the hospital and complications during the hospitalization process.

OBJECTIVE

To identify and analyze the predictors for developing delirium in octogenarians who were admitted to hospital for a hip fracture.

METHODOLOGY

A prospective study conducted with a sample of 287 patients aged 80 years and older (mean age 87.2 ± 3.2 years; 215 women, 72 men), recruited from the Trauma Unit of the University Hospital of León (Spain). Further, 71.1% of the patients lived in a family member's home, while the other 28.9% lived in a nursing home. After observing each patient's interactions with their doctor in a clinical setting, the data for this study were obtained by reviewing the selected patients' charts. The variables analyzed were sociodemographic information (age, sex, and place of residence), medical information (type of hip break and surgical intervention), cognitive impairment (MMSE score), functional level (Barthel Index score), and clinical information (pharmacological, comorbidities, complications, and the diagnosis and assessment of the severity of delirium in a patient). The univariate and multivariate logistic regression analysis showed a significant relationship between acute confusional state and the following variables: anemia, American Society of Anesthesiologists (ASA) III and IV patients, state of cognitive frailty and functional level, a urinary tract infection, changes in the visual field, renal arterial occlusion, and the type and dosage of drugs administered (this variable was identified in the multivariate model). The inverse relationship between anemia and acute confusional state is surprising.

CONCLUSION

This research shows that clinical observation of acute confusional state is necessary but not sufficient for addressing this condition early and adequately in older adults who have been hospitalized for a hip fracture.

摘要

引言

由于谵妄是髋部骨折患者住院后可能出现的主要并发症,它被认为是最常见的老年疾病之一。因此,预防和早期发现谵妄对于缩短患者住院时间以及减少住院过程中的并发症至关重要。

目的

识别并分析因髋部骨折入院的八旬老人发生谵妄的预测因素。

方法

对来自西班牙莱昂大学医院创伤科的287例80岁及以上患者(平均年龄87.2±3.2岁;215名女性,72名男性)进行前瞻性研究。此外,71.1%的患者居住在家庭成员家中,而另外28.9%居住在养老院。在临床环境中观察每位患者与医生的互动后,通过查阅选定患者的病历获取本研究的数据。分析的变量包括社会人口学信息(年龄、性别和居住地点)、医疗信息(髋部骨折类型和手术干预)、认知障碍(简易精神状态检查表评分)、功能水平(巴氏指数评分)以及临床信息(药理学、合并症、并发症以及患者谵妄严重程度的诊断和评估)。单因素和多因素逻辑回归分析显示急性意识模糊状态与以下变量之间存在显著关系:贫血、美国麻醉医师协会(ASA)Ⅲ级和Ⅳ级患者、认知衰弱状态和功能水平、尿路感染、视野改变、肾动脉闭塞以及所用药的类型和剂量(该变量在多因素模型中得以确定)。贫血与急性意识模糊状态之间的负相关关系令人惊讶。

结论

本研究表明,对于因髋部骨折住院的老年人,仅对急性意识模糊状态进行临床观察对于早期充分处理这种情况而言是必要的,但并不充分。

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