Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
J Colloid Interface Sci. 2021 Feb 15;584:92-102. doi: 10.1016/j.jcis.2020.09.125. Epub 2020 Oct 6.
As the applications of supramolecular assemblies are ultimately inscribed in their nanostructures, strategies that can precisely fabricate and regulate supramolecular architectures from small molecules are of great importance. Herein, in this research multiple modulations of supramolecular assembled structures of a natural triterpenoid-tailored bipyridinium amphiphile, 1-[2-(methyl glycyrrhetate)-2-oxoethyl]-[4,4']bipyridinium bromide (MGBP), have been achieved by adjusting solvents or counterions. Depending on the polarity of solvents, MGBP assembled into nanofibers, helices, pentagon and hexagon microsheets, respectively. Moreover, the nanofibers in methanol/water can transform into ribbons, robust fibers and fiber bundles by addition of counterions with different ionic sizes and valences. This work presents a simple and feasible methodology to modulate assembly structures of a natural triterpenoid-based amphiphile, which may expand the application of natural products in supramolecular materials.
由于超分子组装体的应用最终取决于其纳米结构，因此能够精确地从小分子制造和调节超分子结构的策略非常重要。在本研究中，通过调节溶剂或抗衡离子，实现了天然三萜类化合物修饰的双吡啶基两亲分子 1-[2-(甲基甘草次酸)-2-氧代乙基]-[4,4']-联吡啶溴化物（MGBP）的超分子组装结构的多种调制。根据溶剂的极性，MGBP 分别组装成纳米纤维、螺旋体、五边形和六边形微片。此外，甲醇/水中的纳米纤维通过加入具有不同离子大小和价态的抗衡离子，可以转化为带状物、坚固的纤维和纤维束。这项工作提出了一种简单可行的方法来调节基于天然三萜的两亲分子的组装结构，这可能会扩展天然产物在超分子材料中的应用。
