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COVID-19 大流行封锁对妊娠期糖尿病的影响:一项回顾性研究。

Effects of COVID-19 pandemic lockdown on gestational diabetes mellitus: A retrospective study.

机构信息

CHU Lille, Department of Obstetrics, F-59000 Lille, France; University of Lille, CHU Lille, ULR 2694 - METRICS: Assessment of Health Technologies and Medical Practices, F-59000 Lille, France.

CHU Lille, Department of Obstetrics, F-59000 Lille, France; University of Lille, CHU Lille, ULR 2694 - METRICS: Assessment of Health Technologies and Medical Practices, F-59000 Lille, France.

出版信息

Diabetes Metab. 2021 Mar;47(2):101201. doi: 10.1016/j.diabet.2020.09.008. Epub 2020 Oct 15.

Abstract

OBJECTIVE

The objective of our study was to evaluate the impact of the lockdown period on the glycemic balance in patients with GDM.

METHODS

A retrospective study in one center (Lille, France) compared two periods: the COVID-19 lockdown of 18 March 2020 to 7 May 2020 versus the same period during 2019. Glucose targets were defined by a capillary fasting glucose target < 5.1mmol/L and/or a 2-hour postprandial capillary glucose < 6.6 mmol/L. GDM control was defined as: good (< 20% of the glycemic values were not within the target range), acceptable (20 to 40% of the glycemic values were not within the target range) or poor (> 40% of the glycemic values were not within the target range).

RESULTS

Two hundred twenty-nine patients were included in 2019 and 222 in 2020. The same mean number of capillary blood sugar tests was performed by the two groups. Postprandial blood sugar was significantly less well controlled in 2020, with a lower rate of good control (61.6% vs 69.4%) and higher rates of acceptable (24.7% vs 21.8%) and poor control (13.7% and 8.7%) (p < 0.05). Use of insulin therapy was significantly higher in 2020 compared with 2019 (47.7% and 36.2%, respectively; p < 0.05).

CONCLUSION

Diabetes control was lower during the COVID-19 pandemic lockdown, even if follow-up was not impacted. This may be explained by reduced physical activity, modified dietary habits and anxiety during this period.

摘要

目的

本研究旨在评估封锁期对 GDM 患者血糖平衡的影响。

方法

一项单中心回顾性研究(法国里尔)比较了两个时期:2020 年 3 月 18 日至 5 月 7 日的 COVID-19 封锁期与 2019 年同期。血糖目标定义为毛细血管空腹血糖<5.1mmol/L 和/或餐后 2 小时毛细血管血糖<6.6mmol/L。GDM 控制定义为:良好(<20%的血糖值不在目标范围内)、可接受(20%至 40%的血糖值不在目标范围内)或差(>40%的血糖值不在目标范围内)。

结果

2019 年纳入 229 例患者,2020 年纳入 222 例患者。两组均进行了相同数量的毛细血管血糖检测。2020 年餐后血糖控制明显较差,良好控制率较低(61.6%比 69.4%),可接受控制率较高(24.7%比 21.8%)和差控制率较高(13.7%和 8.7%)(p<0.05)。2020 年胰岛素治疗使用率明显高于 2019 年(分别为 47.7%和 36.2%;p<0.05)。

结论

即使随访未受到影响,COVID-19 大流行封锁期间糖尿病控制水平较低。这可能是由于在此期间体力活动减少、饮食习惯改变和焦虑所致。

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