• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

番茄红素和褪黑素:化妆品配方中的抗氧化化合物。

Lycopene and Melatonin: Antioxidant Compounds in Cosmetic Formulations.

机构信息

Faculty of Veterinary from the Department of Physiology, University of Extremadura, Cáceres, Spain.

Faculty of Medicine from the Department of Physiology, University of Extremadura, Badajoz, Spain,

出版信息

Skin Pharmacol Physiol. 2020;33(5):237-243. doi: 10.1159/000508673. Epub 2020 Oct 16.

DOI:10.1159/000508673
PMID:33070140
Abstract

BACKGROUND

The use of antioxidants has become a common practice in the development of antiaging cosmetics.

OBJECTIVE

The aim of this study was to evaluate the clinical efficacy of cosmetic formulations containing lycopene and melatonin antioxidants.

METHOD

Thirty-six healthy women from 32 to 65 years were enrolled in this study. The study was carried out for 10 weeks, 2 preconditioning weeks with a control cream without antioxidants, and 8-week test with creams containing antioxidants in study. A multifunctional skin physiology monitor (Courage & Khazaka electronic GmbH®, Germany) was used to measure skin sebum content, hydration, elasticity, erythema index, and melanin index in 4 different regions of the face.

RESULTS

There were significant differences between them.

摘要

背景

抗氧化剂的使用已成为开发抗衰老化妆品的常见做法。

目的

本研究旨在评估含有番茄红素和褪黑素抗氧化剂的化妆品配方的临床功效。

方法

本研究纳入了 36 名 32 至 65 岁的健康女性。研究进行了 10 周,前 2 周为预条件期,使用不含抗氧化剂的对照霜,第 8 周则使用含有抗氧化剂的研究霜。使用多功能皮肤生理学监测仪(德国 Courage & Khazaka electronic GmbH®)测量面部 4 个不同区域的皮脂含量、水分、弹性、红斑指数和黑色素指数。

结果

它们之间存在显著差异。

相似文献

1
Lycopene and Melatonin: Antioxidant Compounds in Cosmetic Formulations.番茄红素和褪黑素:化妆品配方中的抗氧化化合物。
Skin Pharmacol Physiol. 2020;33(5):237-243. doi: 10.1159/000508673. Epub 2020 Oct 16.
2
Formulation and in-vivo evaluation of a cosmetic multiple emulsion containing vitamin C and wheat protein.含维生素C和小麦蛋白的化妆品多重乳液的配方及体内评价
Pak J Pharm Sci. 2008 Jan;21(1):45-50.
3
Cosmetic benefit of a biomimetic lamellar cream formulation on barrier function or the appearance of fine lines and wrinkles in randomized proof-of-concept clinical studies.在随机概念验证临床研究中,仿生层状乳膏配方对皮肤屏障功能或细纹和皱纹外观的美容效果。
Int J Cosmet Sci. 2019 Feb;41(1):1-11. doi: 10.1111/ics.12499. Epub 2019 Feb 22.
4
In vitro antioxidant activity and in vivo efficacy of topical formulations containing vitamin C and its derivatives studied by non-invasive methods.采用非侵入性方法研究含维生素C及其衍生物的局部用制剂的体外抗氧化活性和体内疗效。
Skin Res Technol. 2008 Aug;14(3):376-80. doi: 10.1111/j.1600-0846.2008.00288.x.
5
Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days.临床证据表明,一种新的 3-in-1 抗衰老局部夜间血清油含有褪黑素、补骨脂酚和抗坏血酸四异棕榈酸酯,具有疗效和安全性:103 名女性接受了 28 至 84 天的治疗。
J Cosmet Dermatol. 2019 Jun;18(3):806-814. doi: 10.1111/jocd.12896. Epub 2019 Mar 28.
6
Human Stem Cell-Derived Skin Progenitors Produce Alpha 2-HS Glycoprotein (Fetuin): A Revolutionary Cosmetic Ingredient.人干细胞衍生的皮肤祖细胞产生α2-HS糖蛋白(胎球蛋白):一种革命性的化妆品成分。
J Drugs Dermatol. 2016 May 1;15(5):583-98.
7
Melatonin reverses the enhanced oxidative damage to membrane lipids and improves skin biophysical characteristics in former-smokers - A study in postmenopausal women.褪黑素可逆转既往吸烟者膜脂质氧化损伤增强的状况,并改善绝经后女性的皮肤生物物理特性——一项研究。
Ann Agric Environ Med. 2017 Dec 23;24(4):659-666. doi: 10.5604/12321966.1235174. Epub 2017 May 11.
8
Comparison of topical antiaging creams in the management of lateral canthal lines.外用抗皱面霜治疗外眦纹的比较
J Cosmet Dermatol. 2020 Mar;19(3):694-704. doi: 10.1111/jocd.13062. Epub 2019 Jul 26.
9
Variation of biophysical parameters of the skin with age, gender, and body region.皮肤生物物理参数随年龄、性别和身体部位的变化。
ScientificWorldJournal. 2012;2012:386936. doi: 10.1100/2012/386936. Epub 2012 Mar 12.
10
Systemic and skin-targeting beneficial effects of lycopene-enriched ice cream: A pilot study.富含番茄红素的冰淇淋对全身和皮肤的有益作用:一项初步研究。
J Dairy Sci. 2019 Jan;102(1):14-25. doi: 10.3168/jds.2018-15282. Epub 2018 Nov 15.

引用本文的文献

1
Corn Steep Liquor as an Efficient Bioresource for Functional Components Production by Biotransformation Technology.玉米浆作为通过生物转化技术生产功能成分的高效生物资源。
Foods. 2025 Jun 20;14(13):2158. doi: 10.3390/foods14132158.
2
The effect of melatonin implants on the embryo yield and oxidative stress levels in superovulated Holstein heifers.褪黑素植入对超排荷斯坦青年母牛胚胎产量和氧化应激水平的影响。
Vet Res Commun. 2025 Jun 24;49(4):236. doi: 10.1007/s11259-025-10807-8.
3
Exploring melatonin's signalling pathways in the protection against age-related skin deterioration.
探索褪黑素在预防与年龄相关的皮肤老化中的信号通路。
Pharmacol Rep. 2025 Apr;77(2):375-391. doi: 10.1007/s43440-025-00699-5. Epub 2025 Jan 30.
4
Melatonin as a multifunctional modulator: emerging insights into its role in health, reproductive efficiency, and productive performance in livestock.褪黑素作为一种多功能调节剂:对其在牲畜健康、繁殖效率和生产性能中作用的新见解。
Front Physiol. 2024 Dec 5;15:1501334. doi: 10.3389/fphys.2024.1501334. eCollection 2024.
5
An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology.关于酚类化合物及其对皮肤生理潜在雌激素特性的广泛综述。
Front Cell Dev Biol. 2024 Jan 4;11:1305835. doi: 10.3389/fcell.2023.1305835. eCollection 2023.
6
In Vitro and In Vivo Characteristics of Olive Oil as Excipient for Topical Administration.橄榄油作为局部给药辅料的体外和体内特性
Pharmaceutics. 2022 Nov 26;14(12):2615. doi: 10.3390/pharmaceutics14122615.
7
Cosmeceutical Therapy: Engaging the Repercussions of UVR Photoaging on the Skin's Circadian Rhythm.美容护肤疗法:应对 UVR 光老化对皮肤昼夜节律的影响。
Int J Mol Sci. 2022 Mar 7;23(5):2884. doi: 10.3390/ijms23052884.
8
Promising Natural Products in New Drug Design, Development, and Therapy for Skin Disorders: An Overview of Scientific Evidence and Understanding Their Mechanism of Action.有前景的天然产物在新药设计、开发和皮肤疾病治疗中的应用:对科学证据的概述及对其作用机制的理解。
Drug Des Devel Ther. 2022 Jan 6;16:23-66. doi: 10.2147/DDDT.S326332. eCollection 2022.