Exogenous ketones in the healthy heart: the plot thickens.
作者信息
Selvaraj Senthil, Margulies Kenneth B
机构信息
Division of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Cardiovascular Institute and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
出版信息
Cardiovasc Res. 2021 Mar 21;117(4):995-996. doi: 10.1093/cvr/cvaa283.
Abstract
摘要
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本文引用的文献
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Circulation. 2020 Jun 2;141(22):1800-1812. doi: 10.1161/CIRCULATIONAHA.119.045033. Epub 2020 Jun 1.
2
Ketones can become the major fuel source for the heart but do not increase cardiac efficiency.酮体可以成为心脏的主要燃料来源，但不会提高心脏效率。
Cardiovasc Res. 2021 Mar 21;117(4):1178-1187. doi: 10.1093/cvr/cvaa143.
3
Cardiovascular Effects of Treatment With the Ketone Body 3-Hydroxybutyrate in Chronic Heart Failure Patients.治疗慢性心力衰竭患者酮体 3-羟丁酸的心血管效应。
Circulation. 2019 Apr 30;139(18):2129-2141. doi: 10.1161/CIRCULATIONAHA.118.036459.
4
Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency.酮体氧化增加为衰竭的心脏提供了额外的能量，而不改善心脏效率。
Cardiovasc Res. 2019 Sep 1;115(11):1606-1616. doi: 10.1093/cvr/cvz045.
5
The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.衰竭的心脏利用 3-羟基丁酸作为代谢应激防御。
JCI Insight. 2019 Feb 21;4(4). doi: 10.1172/jci.insight.124079.
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Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes.营养性酮症改变燃料偏好，从而提高运动员的耐力表现。
Cell Metab. 2016 Aug 9;24(2):256-68. doi: 10.1016/j.cmet.2016.07.010. Epub 2016 Jul 27.
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Insulin Signaling and Heart Failure.胰岛素信号传导与心力衰竭
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Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.评估心脏代谢：美国心脏协会的科学声明。
Circ Res. 2016 May 13;118(10):1659-701. doi: 10.1161/RES.0000000000000097. Epub 2016 Mar 24.
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The Failing Heart Relies on Ketone Bodies as a Fuel.衰竭心脏依赖酮体作为燃料。
Circulation. 2016 Feb 23;133(8):698-705. doi: 10.1161/CIRCULATIONAHA.115.017355. Epub 2016 Jan 27.
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Circulation. 2016 Feb 23;133(8):706-16. doi: 10.1161/CIRCULATIONAHA.115.017545. Epub 2016 Jan 27.
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