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[体温过低期后早期脑组织中的肽水解酶活性]

[Peptide hydrolase activity in brain tissues during the early stages of post-hypothermia period].

作者信息

Nurmagomedova P M

出版信息

Ukr Biokhim Zh (1978). 1987 Jul-Aug;59(4):91-3.

PMID:3307080
Abstract

The acid peptidohydrolase activity in the homogenate, dissoluble and mitochondrial-lysosomal fractions of brain tissues of rats who have endured deep hypothermia was determined after their "active" warming for an hour and on the 1st, 2nd, 3d and 7th days after their self-warming. The "active" warming of rats who have endured deep hypothermia (19-20 degrees C) brings about the restoration of the acid peptidohydrolase activity in the subcellular brain tissue fractions. After self-warming the examined enzyme activity restores 7 days later. In the dynamics of the posthypothermic period a change in the acid peptide hydrolase distribution in fractions occurs on the 2nd-3d days.

摘要

在经历深度低温的大鼠脑组织匀浆、可溶部分以及线粒体 - 溶酶体部分中,测定了在其“主动”复温1小时后以及自行复温后第1、2、3和7天的酸性肽水解酶活性。经历深度低温(19 - 20摄氏度)的大鼠“主动”复温会使脑组织亚细胞部分的酸性肽水解酶活性恢复。自行复温后,所检测的酶活性在7天后恢复。在低温后时期的动态变化中,第2 - 3天各部分酸性肽水解酶的分布发生改变。

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