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[缺氧对伴有和不伴有低温的大鼠脑肽水解酶活性的影响]

[Effects of oxygen deficiency on rat brain peptide-hydrolase activity with and without hypothermia].

作者信息

Malikov U M, Panov A N, Shmelev A A

出版信息

Ukr Biokhim Zh (1978). 1978 Sep-Oct;50(5):579-81.

PMID:31720
Abstract

The effect of acute oxygen deficiency on the rat brain peptide-hydrolases (EC 3.4) activity was studied under conditions of acute hypoxic hypoxia (the pressure in altitude chamber 240 mm Hg) with concomitant hypothermia (--5.8 degree C) and without it. The activity of neutral peptide hydrolases decreases by 29% in rats with hypothermia, in animals with normothermia remains unchanged. The activity of acid peptide hydrolases was the control level. The data obtained are compared with those relative to preservation of the content of soluble proteins under hypoxia with hypothermia.

摘要

在伴有体温过低(-5.8摄氏度)和不伴有体温过低的急性低氧性缺氧(海拔舱压力240毫米汞柱)条件下,研究了急性缺氧对大鼠脑肽水解酶(EC 3.4)活性的影响。伴有体温过低的大鼠中性肽水解酶活性降低29%,体温正常的动物该活性保持不变。酸性肽水解酶活性处于对照水平。将所得数据与体温过低时缺氧条件下可溶性蛋白质含量保存情况的相关数据进行了比较。

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