Su Yana, Cui Li, Zhu Mingqin, Liang Yixuan, Zhang Ying
Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Front Neurol. 2020 Sep 18;11:1017. doi: 10.3389/fneur.2020.01017. eCollection 2020.
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is part of the variant type of the Stiff Person Syndrome (SPS) and is a rare neurological disease. We report here a patient with PERM who had thymoma and was positive for anti-glutamic acid decarboxylase (anti-GAD) antibodies. Her symptoms improved after treatment with hormones and gamma globulin. We also summarized the literature review of patients with PERM accompanied by tumors reported.
进行性脑脊髓炎伴强直和肌阵挛(PERM)是僵人综合征(SPS)变异型的一部分,是一种罕见的神经系统疾病。我们在此报告一例患有胸腺瘤且抗谷氨酸脱羧酶(抗GAD)抗体呈阳性的PERM患者。经激素和γ球蛋白治疗后,她的症状有所改善。我们还总结了已报道的伴有肿瘤的PERM患者的文献综述。