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伴胸腺瘤的进行性脑脊髓炎伴强直和肌阵挛:一例报告及文献复习

Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review.

作者信息

Su Yana, Cui Li, Zhu Mingqin, Liang Yixuan, Zhang Ying

机构信息

Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.

出版信息

Front Neurol. 2020 Sep 18;11:1017. doi: 10.3389/fneur.2020.01017. eCollection 2020.

Abstract

Progressive encephalomyelitis with rigidity and myoclonus (PERM) is part of the variant type of the Stiff Person Syndrome (SPS) and is a rare neurological disease. We report here a patient with PERM who had thymoma and was positive for anti-glutamic acid decarboxylase (anti-GAD) antibodies. Her symptoms improved after treatment with hormones and gamma globulin. We also summarized the literature review of patients with PERM accompanied by tumors reported.

摘要

进行性脑脊髓炎伴强直和肌阵挛(PERM)是僵人综合征(SPS)变异型的一部分,是一种罕见的神经系统疾病。我们在此报告一例患有胸腺瘤且抗谷氨酸脱羧酶(抗GAD)抗体呈阳性的PERM患者。经激素和γ球蛋白治疗后,她的症状有所改善。我们还总结了已报道的伴有肿瘤的PERM患者的文献综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2092/7533529/e6e7eefd99e9/fneur-11-01017-g0001.jpg

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