Department of Clinical Sciences, Family Medicine Malmö, Lund University, Malmö, Sweden.
Futurum, Jönköping, Sweden.
Infect Dis (Lond). 2021 Feb;53(2):94-101. doi: 10.1080/23744235.2020.1834138. Epub 2020 Oct 19.
Uncomplicated urinary tract infection (UTI) causes bothersome symptoms among women and is a leading cause for antibiotic prescribing in primary healthcare (PHC).
A prospective observational study in eight different PHC centres in Sweden including 192 women with symptoms of uncomplicated UTI. Questionnaires and symptom diaries were used to retrieve patient data. All urine samples were analysed with urine culture and susceptibility testing. The aim was to describe the clinical presentation of symptoms in uncomplicated UTI in relation to bacterial findings in urine and to describe the course and duration of symptoms in relation to anamnestic factors, bacterial findings and antibiotic treatment.
Median symptom duration before seeking care was four days (IQR 1-7). Restrictions in daily life related to symptoms of uncomplicated UTI were reported by the majority (74%) of respondents. The median number of days concerning any symptom after consultation was 4.0 days (IQR 2.0-5.0) for patients treated with antibiotics, and 6.5 days (IQR 3.0-10.0) for patients not treated with antibiotics. There was an association between longer symptom duration after consultation and age over 50 years, relative risk (RR) 1.76 (95% CI 1.25-2.49). Antibiotic treatment RR 0.47 (95% CI 0.27-0.81) was associated with reported shorter duration of symptoms.
Women visiting primary health care with symptoms indicating uncomplicated UTI have symptoms for several days before seeking care and after consulting. A majority of patients feel restricted in their daily activities due to uncomplicated UTI. Older women and women not treated with antibiotics have the longest symptom duration after consultation.
单纯性尿路感染(UTI)会给女性带来不适症状,是基层医疗保健(PHC)中开具抗生素的主要原因。
这是一项在瑞典 8 个不同 PHC 中心进行的前瞻性观察性研究,共纳入 192 例有单纯性 UTI 症状的女性。使用问卷和症状日记来获取患者数据。所有尿液样本均进行尿液培养和药敏试验分析。目的是描述单纯性 UTI 症状的临床表现与尿液中细菌发现之间的关系,并描述症状的病程和持续时间与病史因素、细菌发现和抗生素治疗之间的关系。
在寻求医疗护理前,症状持续时间的中位数为 4 天(IQR 1-7)。大多数(74%)受访者报告称,单纯性 UTI 症状会限制日常生活。接受抗生素治疗的患者在咨询后出现任何症状的天数中位数为 4.0 天(IQR 2.0-5.0),未接受抗生素治疗的患者为 6.5 天(IQR 3.0-10.0)。咨询后症状持续时间较长与年龄大于 50 岁有关,相对风险(RR)为 1.76(95% CI 1.25-2.49)。抗生素治疗的 RR 为 0.47(95% CI 0.27-0.81)与报告的症状持续时间较短相关。
因单纯性 UTI 症状就诊于基层医疗保健的女性在寻求医疗护理前和咨询后都会出现数日的症状。大多数患者因单纯性 UTI 而感到日常活动受限。年龄较大的女性和未接受抗生素治疗的女性在咨询后症状持续时间最长。