Wilkins I A, Chitkara U, Lynch L, Goldberg J D, Mehalek K E, Berkowitz R L
Am J Obstet Gynecol. 1987 Sep;157(3):694-8. doi: 10.1016/s0002-9378(87)80031-5.
Fetal urine was sampled 12 times in nine fetuses with sonographically diagnosed urinary tract obstruction to assess renal function. By previously proposed criteria, four fetuses were predicted to have poor renal function. Two of these fetuses were found to have renal dysplasia on autopsy after elective termination. The other two died in the neonatal period but only one of these had histologic evidence of renal dysplasia. Five fetuses were predicted to have good renal function. Three of these developed renal failure after birth, one was found to have renal dysplasia on autopsy after elective termination, and one is alive and well. We conclude that fetal urine electrolytes are not necessarily an accurate predictor of neonatal renal function.
对9例经超声诊断为尿路梗阻的胎儿的尿液进行了12次采样，以评估肾功能。根据先前提出的标准，预测4例胎儿肾功能不佳。其中2例胎儿在选择性终止妊娠后尸检发现有肾发育不全。另外2例在新生儿期死亡，但其中只有1例有肾发育不全的组织学证据。5例胎儿被预测肾功能良好。其中3例出生后出现肾衰竭，1例在选择性终止妊娠后尸检发现有肾发育不全，1例存活且状况良好。我们得出结论，胎儿尿液电解质不一定是新生儿肾功能的准确预测指标。
