Department of Public Health, and Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, China.
Int J Psychiatry Clin Pract. 2021 Nov;25(4):367-374. doi: 10.1080/13651501.2020.1828930. Epub 2020 Oct 19.
We described the changing patterns of depression and anxiety status in different trimesters among Chinese pregnant women, and identified the modified form of SDS/SAS for pregnant women and assessed its reliability and validity.
Changing patterns of depression/ anxiety status in different trimesters were described. The modified form of SDS/SAS was identified for pregnant women. Cohen's Kappa to measure agreement with SDS/SAS, and the ROC analysis was performed to assess its validity.
The SDS score in 1st trimester was higher than 2nd and 3rd trimester; there was no significant difference between SDS score in 2nd and 3rd trimester. Modified form of SDS evaluated the depression; the areas under the curve (AUC) in testing group were up to 0.988, 0.989 and 0.992 for 1st, 2nd and 3rd trimester, respectively. Modified form of SAS evaluated the anxiety, the AUC in testing group were up to 0.987, 0.985, 0.987 for 1st, 2nd and 3rd trimester, respectively.
Pregnant women had higher severity of depression and anxiety status in 1st trimester than that in 2nd and 3rd trimester. The modified form of SDS/SAS may be more brief and suitable to assess the depression and anxiety status in pregnant women.KEY POINTSPregnant women had a higher severity of depression and anxiety status in the 1st trimester than that in the 2nd and 3rd trimester.The present study suggests that prenatal depression and anxiety status are prevalent in Chinese pregnant women.Prevention or treatments focus on high-score items of SDS and SAS would be beneficial for rectifying prenatal depression and anxiety.
我们描述了中国孕妇在不同孕期抑郁和焦虑状态的变化模式，并确定了适合孕妇的 SDS/SAS 修正版，并评估了其信度和效度。
描述不同孕期抑郁/焦虑状态的变化模式。确定适合孕妇的 SDS/SAS 修正版。采用 Cohen's Kappa 评估 SDS/SAS 的一致性，进行 ROC 分析评估其效度。
第 1 孕期 SDS 评分高于第 2 和第 3 孕期；第 2 和第 3 孕期 SDS 评分无显著差异。修正版 SDS 评估抑郁；试验组第 1、2、3 孕期的曲线下面积（AUC）分别为 0.988、0.989 和 0.992。修正版 SAS 评估焦虑，试验组第 1、2、3 孕期的 AUC 分别为 0.987、0.985、0.987。
孕妇在第 1 孕期的抑郁和焦虑严重程度高于第 2 和第 3 孕期。SDS/SAS 修正版可能更简洁，适用于评估孕妇的抑郁和焦虑状态。
孕妇在第 1 孕期的抑郁和焦虑严重程度高于第 2 和第 3 孕期。
本研究表明，中国孕妇产前抑郁和焦虑的发生率较高。
针对 SDS 和 SAS 的高分项目进行预防或治疗可能有助于纠正产前抑郁和焦虑。
