Wu Qichang, Chen Jiebing, Zou Qiaojian, Zeng Xun, Yang Yan, Zhou Yijia, He Guimei, Luo Chunqi, Wu Fengchun
Department of Outpatient, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Front Psychiatry. 2022 Apr 6;13:764345. doi: 10.3389/fpsyt.2022.764345. eCollection 2022.
To analyze the anxiety, depression, and related factors among pregnant women with cervical insufficiency, so as to provide a reference for clinical psychological intervention as an adjuvant therapy.
A total of 101 cases in China with cervical insufficiency were included in the observation group by a convenience sampling method, and 114 normal healthy women of childbearing age were selected as the control group. Participants were investigated and observed for anxiety and depression by SAS and SDS, respectively, to analyze the emotional state and influencing factors of the patients with cervical insufficiency. Stratified by the first, second and third trimesters, our study used whether depressive or not and whether anxiety or not as the dichotomous variables. A multivariate Logistic regression was adopted to analyze the influencing factors. Relevant influencing factors were screened out by the forward stepwise method in combination with professional knowledge and the number of variables.
There were statistical significant differences in SAS and SDS between observation group and control group and the incidence rate of anxiety and depression was higher in pregnant women with CI. Multivariate Logistic regression demonstrated that history of abnormal pregnancy was the main influencing factor for anxiety and depression in the early and middle gestation phases, and cervical insufficiency was the factor influencing the anxiety in early gestation and both anxiety and depression in the late gestation phase.
Cervical insufficiency may have a negative impact on the emotions of pregnant women. Individualized and targeted mental care should be added into clinic work to prevent negative outcomes.
分析宫颈机能不全孕妇的焦虑、抑郁及相关因素，为临床心理干预作为辅助治疗提供参考。
采用便利抽样法选取我国101例宫颈机能不全患者作为观察组，选取114例正常健康育龄妇女作为对照组。分别采用SAS和SDS对参与者进行焦虑和抑郁调查观察，分析宫颈机能不全患者的情绪状态及影响因素。本研究按孕早、中、晚期进行分层，以是否抑郁和是否焦虑作为二分变量。采用多因素Logistic回归分析影响因素。结合专业知识和变量数量，采用向前逐步法筛选相关影响因素。
观察组与对照组的SAS和SDS评分差异有统计学意义，宫颈机能不全孕妇的焦虑和抑郁发生率更高。多因素Logistic回归分析显示，妊娠异常史是孕早、中期焦虑和抑郁的主要影响因素，宫颈机能不全是孕早期焦虑及孕晚期焦虑和抑郁的影响因素。
宫颈机能不全可能对孕妇情绪产生负面影响。临床工作中应增加个体化、有针对性的心理护理措施，以预防不良后果。
