VanEpps D E, Tung K S
J Immunol. 1977 Sep;119(3):1187-9.
Fucose-binding L. tetragonolobus lectin to the surface of human polymorphonuclear leukocytes (PMN) and induces a chemotactic response. Both surface binding and chemotaxis are inhibited by free fucose but not by fructose, mannose, or galactose. The lectin-binding sites on PMN are unrelated to the A, B, or O blood group antigen. Utilization of this lectin should be a useful tool in isolating PMN membrane components and in analyzing the mechanism of neutrophil chemotaxis.
岩藻糖结合的四角豆凝集素可结合到人多形核白细胞（PMN）表面并诱导趋化反应。表面结合和趋化作用均受到游离岩藻糖的抑制，但不受果糖、甘露糖或半乳糖的抑制。PMN上的凝集素结合位点与A、B或O血型抗原无关。利用这种凝集素应是分离PMN膜成分和分析中性粒细胞趋化机制的有用工具。
