Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, 94305, USA.
Division of Maternal-Fetal Medicine and Obstetrics, Department of Obstetrics and Gynecology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA.
Placenta. 2021 Jan 1;103:50-52. doi: 10.1016/j.placenta.2020.10.018. Epub 2020 Oct 13.
Umbilical cord blood is an important graft source in the treatment of many genetic, hematologic, and immunologic disorders by hematopoietic stem cell transplantation. Millions of cord blood units have been collected and stored for clinical use since the inception of cord blood banking in 1989. However, the use of cord blood in biomedical research has been limited by access to viable samples. Here, we present a cost-effective, self-sustaining model for the procurement of fresh umbilical cord blood components for research purposes within hospital-affiliated academic institutions.
脐带血是造血干细胞移植治疗许多遗传、血液和免疫疾病的重要移植物来源。自 1989 年脐带血库建立以来，已经收集和储存了数百万份脐带血单位，用于临床应用。然而，由于获取可行的样本，脐带血在生物医学研究中的应用受到限制。在这里，我们提出了一种具有成本效益的、可持续的模型，用于在医院附属学术机构中为研究目的采购新鲜的脐带血成分。
