Książczyk Tomasz M, Pietrzak Radosław, Werner Bożena
Department of Paediatric Cardiology and General Paediatrics, Medical University of Warsaw, 02-091 Warsaw, Poland.
Diagnostics (Basel). 2020 Oct 15;10(10):824. doi: 10.3390/diagnostics10100824.
The management of young athletes with asymptomatic preexcitation remains a challenge, regardless of the progress we have made in understanding the basis of condition and developing catheter ablation procedures. The risk of sudden death, however small, yet definite, being the first symptom is determining our approach. The aim of the study was to establish the current state of knowledge regarding the management of young athletes diagnosed with asymptomatic preexcitation, by conducting a literature review.
A comprehensive literature review was completed in accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The search was limited to English language publications using the following search terms: "asymptomatic" or "incidental" and "pre-excitation" or "Wolff-Parkinson-White" or "delta wave" and "athlete" or "sport". The search was supplemented by hand review of the bibliographies of previous relevant systematic reviews.
The search resulted in 85 of abstracts, and the manual search of the bibliographies resulted in 24 additional papers. After careful analysis 10 publications were included in the review. In all but one of the presented papers, the authors used non-invasive methods and then either trans-esophageal or invasive EPS as a way to risk stratify asymptomatic patients. Evidence of rapid conduction through the accessory pathway was considered high risk and prompted sport disqualification. In the analysed reports there were combined: 142 episodes of the life-threatening events (LTE)/sudden death (SCD), of which 56 were reported to occur at rest, 61 during activity and no data were available for 25.
athletic activity may impose an increased risk of life-threatening arrhythmias in patients with asymptomatic preexcitation; hence, a separate approach could be considered, especially in patients willing to engage in high-intensity, endurance and competitive sports.
无论我们在理解无症状预激综合征的发病机制以及开发导管消融手术方面取得了多大进展,年轻无症状预激综合征运动员的管理仍然是一项挑战。然而,猝死风险虽小但确切存在,作为首发症状决定了我们的处理方式。本研究的目的是通过文献综述来确定目前关于诊断为无症状预激综合征的年轻运动员管理的知识现状。
根据系统评价和荟萃分析的首选报告项目(PRISMA)指南完成了全面的文献综述。搜索仅限于英文出版物,使用以下搜索词:“无症状”或“偶然发现”以及“预激”或“ Wolff-Parkinson-White综合征”或“δ波”以及“运动员”或“运动”。通过人工查阅先前相关系统评价的参考文献进行补充搜索。
搜索得到85篇摘要,人工查阅参考文献又得到24篇论文。经过仔细分析,10篇出版物被纳入综述。在所呈现的论文中,除了一篇之外,作者均使用非侵入性方法,然后将经食管或侵入性电生理检查作为对无症状患者进行风险分层的方法。通过旁路快速传导的证据被认为是高风险,并促使运动员被取消比赛资格。在分析的报告中,共合并了142例危及生命的事件(LTE)/心源性猝死(SCD),其中56例据报道发生在休息时,61例发生在活动期间,并25例无相关数据。
运动可能会增加无症状预激综合征患者发生危及生命心律失常的风险;因此,可以考虑采用单独的处理方法,特别是对于那些愿意参加高强度、耐力和竞技性运动的患者。