Mochiji Mihoko, Kaidzu Sachiko, Ishiba Yoshihisa, Matsuda Yuji, Tanito Masaki
Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo 693-8501, Japan.
Technology Development Department, Yamamoto Kogaku Co. Ltd., Higashi-Osaka 577-0056, Japan.
Materials (Basel). 2020 Oct 15;13(20):4593. doi: 10.3390/ma13204593.
Intraocular stability during or after cataract and glaucoma filtration surgeries and vitreous surgery with a gas/silicone oil tamponade might differ among intraocular lenses (IOLs). We used six different one-piece IOL models and measured the force that displaced the IOLs from the vitreous cavity to anterior chamber as a measure of stability against the pressure gradient between the anterior and posterior IOL surfaces. We measured IOL hardness, haptics junction area, and posterior IOL bulge to identify what determines the IOL displacement force. The KOWA YP2.2 IOL (1.231 mN) required significantly greater force than the HOYA XY1 (0.416 mN, = 0.0004), HOYA 255 (0.409 mN, = 0.0003), Alcon SN60WF (0.507 mN, = 0.0010), and Nidek NS60YG (0.778 mN, = 0.0186) IOLs; J&J ZCB00V IOL (1.029 mN) required greater force than the HOYA XY1 ( = 0.0032) and HOYA 255 ( = 0.0029) IOLs; the Nidek NS60YG IOL required greater force than the HOYA 255 ( = 0.0468) IOL. The haptics junction area was correlated positively with the IOL displacement force ( = 0.8536, = 0.0306); the correlations of the other parameters were non-significant. After adjusting for any confounding effects, the haptics junction area was correlated significantly with the IOL displacement force ( = 0.0394); the IOL hardness ( = 0.0573) and posterior IOL bulge ( = 0.0938) were not. The forces that displace IOLs anteriorly differed among one-piece soft-acrylic IOLs, and the optics/haptics junction area was the major force determinant.
在白内障和青光眼滤过手术期间或术后以及使用气体/硅油填塞的玻璃体手术中，眼内稳定性在不同的人工晶状体（IOL）之间可能存在差异。我们使用了六种不同的一体式IOL模型，并测量了将IOL从玻璃体腔移位到前房的力，以此作为抵抗IOL前后表面之间压力梯度的稳定性指标。我们测量了IOL硬度、襻连接面积和IOL后凸，以确定是什么决定了IOL移位力。KOWA YP2.2 IOL（1.231 mN）所需的力明显大于HOYA XY1（0.416 mN，P = 0.0004）、HOYA 255（0.409 mN，P = 0.0003）、Alcon SN60WF（0.507 mN，P = 0.0010）和Nidek NS60YG（0.778 mN，P = 0.0186）IOL；强生ZCB00V IOL（1.029 mN）所需的力大于HOYA XY1（P = 0.0032）和HOYA 255（P = 0.0029）IOL；Nidek NS60YG IOL所需的力大于HOYA 255（P = 0.0468）IOL。襻连接面积与IOL移位力呈正相关（r = 0.8536，P = 0.0306）；其他参数的相关性不显著。在调整任何混杂效应后，襻连接面积与IOL移位力显著相关（P = 0.0394）；IOL硬度（P = 0.0573）和IOL后凸（P = 0.0938）则不然。一体式软丙烯酸IOL向前移位IOL的力各不相同，光学部/襻连接面积是主要的力决定因素。
