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人工晶状体眼内无可检测到的眼内异物的铁质沉着性青光眼：一例报告

Siderotic glaucoma without detectable intraocular foreign body in a pseudophakic eye: a case report.

作者信息

Huang Yang, Ye Zi, Li Zhaohui

机构信息

Department of Ophthalmology, The Chinese People's Liberation Army General Hospital, No.28 Fuxing Road Haidian District, Beijing, China.

出版信息

BMC Ophthalmol. 2020 Oct 19;20(1):417. doi: 10.1186/s12886-020-01691-8.

DOI:10.1186/s12886-020-01691-8
PMID:33076842
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7574297/
Abstract

BACKGROUND

Ocular siderosis is induced by a retained intraocular foreign body (IOFB) containing iron and can present as siderotic glaucoma. We report a rare case of histopathologically proven siderotic glaucoma in a middle-aged blacksmith with a preceding history of ocular trauma but no radiologically detectable IOFB.

CASE PRESENTATION

A 42-year-old blacksmith presented with an elevation of intraocular pressure (IOP) in left eye showing iris heterochromia and brownish deposits throughout the trabecular meshwork (TM). Preoperative ophthalmic examination did not reveal any retained IOFBs. Electroretinography showed the classic changes of retinal degeneration in ocular siderosis. Histopathologic staining of the TM verified the presence of iron deposits.

CONCLUSION

This case underlines the importance of the close monitoring of patients with a history of ocular trauma and highlights the necessity of electroretinography, histopathologic study, and detailed ophthalmic examination in the diagnosis of siderotic glaucoma, even if there is no definite radiologically detectable IOFB.

摘要

背景

眼铁质沉着症由眼内残留含铁异物（IOFB）引起，可表现为铁质沉着性青光眼。我们报告一例罕见的组织病理学证实的铁质沉着性青光眼病例，患者为中年铁匠，有眼外伤史，但影像学检查未发现可检测到的IOFB。

病例介绍

一名42岁的铁匠因左眼眼压升高就诊，检查发现虹膜异色以及小梁网（TM）有褐色沉积物。术前眼科检查未发现任何残留的IOFB。视网膜电图显示眼铁质沉着症中视网膜变性的典型变化。TM的组织病理学染色证实存在铁沉积。

结论

该病例强调了对有眼外伤史患者进行密切监测的重要性，并突出了视网膜电图、组织病理学研究和详细眼科检查在铁质沉着性青光眼诊断中的必要性，即使没有明确的影像学可检测到的IOFB。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eee/7574297/8e2a66c8701d/12886_2020_1691_Fig10_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eee/7574297/291ec4cc6b6a/12886_2020_1691_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eee/7574297/2f6e37b68676/12886_2020_1691_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eee/7574297/d34d9ea92f7e/12886_2020_1691_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eee/7574297/8e2a66c8701d/12886_2020_1691_Fig10_HTML.jpg

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BMC Ophthalmol. 2017 Mar 14;17(1):26. doi: 10.1186/s12886-017-0424-4.
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