Corbett W T, Berkhoff H A, Vinal A C
Department of Microbiology, Pathology and Parasitology, School of Veterinary Medicine, North Carolina State University, Raleigh 27606.
Can J Vet Res. 1987 Jul;51(3):312-5.
An epidemiological prospective (longitudinal) study design was used to evaluate the association of Congo red positive Escherichia coli and avian colisepticemia. High and low risk exposure groups of chickens were identified at hatching, and placed in separate identical houses on the same farm. Approximately 14,000 birds were placed in each house for the seven week grow-out period, during which all birds which died were necropsied and cultured, together with a representative sample of birds which were culled weekly. The findings implicated Escherichia coli as the etiological agent of avian colisepticemia. A relative risk of 6.5 and attributable risk of 73.5% supported the hypothesis that the Congo red medium identifies a virulent form of Escherichia coli which causes airsacculitis-colisepticemia in poultry.
采用流行病学前瞻性（纵向）研究设计来评估刚果红阳性大肠杆菌与禽败血病之间的关联。在孵化时确定了高风险和低风险暴露组的鸡，并将它们安置在同一农场中单独的相同鸡舍里。在为期7周的育成期内，每个鸡舍大约饲养14000只鸡，在此期间，对所有死亡的鸡进行尸检和培养，并每周对一批代表性的淘汰鸡进行同样处理。研究结果表明大肠杆菌是禽败血病的病原体。相对风险为6.5，归因风险为73.5%，这支持了以下假设：刚果红培养基可识别出一种导致家禽气囊炎-败血病的致病性大肠杆菌。
