Murphy M N, Dhalla S S, Diocee M, Halliday W, Wiseman N E, deSa D J
Department of Pathology, Health Sciences Centre, Winnipeg, Manitoba, Canada.
Clin Neuropathol. 1987 Jul-Aug;6(4):169-73.
We describe a case of congenital ependymoblastoma presenting as a subcutaneous mass in the sacrococcygeal area of a newborn male. The tumor was composed of primitive cells disposed in compact sheets and cords and exhibiting focal ependymal differentiation. No other line of cellular differentiation was identified by either immunohistochemistry or ultrastructural study. Elevated serum alpha-fetoprotein was found, which decreased following surgical extirpation of the tumor. We propose that this tumor had its origin in the ependymal medullary vestige, similar to other sacrococcygeal ependymomas.
我们描述了一例先天性室管膜母细胞瘤，表现为一名新生儿男性骶尾部皮下肿块。肿瘤由排列紧密的片状和条索状原始细胞组成，并显示局灶性室管膜分化。免疫组化或超微结构研究均未发现其他细胞分化谱系。发现血清甲胎蛋白升高，肿瘤手术切除后其水平下降。我们认为该肿瘤起源于室管膜髓质遗迹，与其他骶尾部室管膜瘤相似。
