Salah-Mabed Imene, Moran Sarah, Perez Emmanuelle, Debellemanière Guillaume, Gatinel Damien
Department of Anterior Segment and Refractive Surgery, Rothschild Foundation, Paris, France.
Center of Expertise and Research in Optics for Clinicians, Stanford, CA, USA.
J Ophthalmol. 2020 Oct 3;2020:7296412. doi: 10.1155/2020/7296412. eCollection 2020.
To evaluate changes in corneal anatomy and quality of vision following LASIK refractive surgery for mild to high myopia using the WaveLight® Refractive Suite (Alcon® Laboratories Inc., USA). . Rothschild Foundation, Paris, France.
Prospective interventional case series.
We examined 60 myopic eyes (average SE -4.5 D, from -9.3 to -0.75 D) of 30 patients from 21.3 to 38.7 years old. Pachymetry, keratometry, factor, corneal aberrations, visual acuity (VA), contrast sensitivity, dry eye assessment, and quality of vision were measured preoperatively, one day (D1), and 1, 3, and 6 months postoperatively.
6 months postoperatively, keratometry became flatter, and the factor became more oblate (from -0.18 ± 0.08 to +0.19 ± 0.06). Pachymetry decreased by 117.9 ± 62.2 m at D1 and increased by 37.87 ± 32.6 m between D1 and M6. Refraction was emmetropic at D1 and remained stable thereafter. Six months after surgery, VA was slightly but nonsignificantly improved (<0.05 log MAR), whereas contrast sensitivity remained unchanged. Quality of vision was not affected by surgery and was more related to dry eye symptoms than to corneal HOAs ( = 0.49; < 0.001 vs. = 0.03; < 0.001).
LASIK surgery for moderate to high myopia, performed with the WaveLight® Refractive Suite, showed good postoperative outcomes, with demonstrated safety, predictability, efficiency, and stability. This is probably due to well-controlled spherical aberration and the use of large optical zones. Besides, we can assume that the patients' quality of vision depends more on the postoperative dry eye disease generated by the laser than on the induced HOAs.
使用威视®屈光手术平台(美国爱尔康公司)评估准分子激光原位角膜磨镶术(LASIK)治疗轻至高度近视后角膜解剖结构和视力质量的变化。法国巴黎罗斯柴尔德基金会。
前瞻性干预性病例系列研究。
我们检查了30例年龄在21.3至38.7岁之间的近视患者的60只眼睛(平均等效球镜度数-4.5D,范围为-9.3至-0.75D)。术前、术后1天(D1)以及术后1、3和6个月测量角膜厚度、角膜曲率、Q值、角膜像差、视力(VA)、对比敏感度、干眼评估和视觉质量。
术后6个月,角膜曲率变平,Q值变得更扁(从-0.18±0.08变为+0.19±0.06)。角膜厚度在D1时减少了117.9±62.2μm,在D1至M6之间增加了37.87±32.6μm。术后1天屈光状态为正视,此后保持稳定。术后6个月,视力略有改善但无显著差异(<logMAR 0.05),而对比敏感度保持不变。视觉质量不受手术影响,与干眼症状的相关性大于与角膜高阶像差的相关性(r = 0.49;P < 0.001 vs. r = 0.03;P < 0.001)。
使用威视®屈光手术平台进行的中高度近视LASIK手术显示出良好的术后效果,具有安全性、可预测性、有效性和稳定性。这可能归因于良好控制的球差和大光学区的使用。此外,我们可以认为患者的视觉质量更多地取决于激光引起的术后干眼疾病,而不是诱导的高阶像差。