Wexner S D, Attiyeh F F
Department of Surgery, Roosevelt Hospital, New York, New York.
Dis Colon Rectum. 1987 Oct;30(10):812-5. doi: 10.1007/BF02554634.
Mesenteric panniculitis is an extremely rare disease in which the normal fatty architecture of the mesentery is replaced by fibrosis, necrosis, and calcification. Grossly, the mesentery is massively thickened and rubbery, with irregular areas of reddish-brown to pale yellow foci resembling fat necrosis scattered throughout. Microscopically, inflammatory involvement of the fibroadipose tissue shows round cells, foam cells, and giant cells. Macrophages that have ingested fat, also called lipophages, are the hallmark of the diagnosis. One hundred twenty-two cases of mesenteric panniculitis have been described in the literature; only three of these involved the large-bowel mesentery. This paper presents a review of the literature and two new cases that involve exclusively the mesentery of the sigmoid colon.
肠系膜脂膜炎是一种极为罕见的疾病，其中肠系膜的正常脂肪结构被纤维化、坏死和钙化所取代。大体上，肠系膜明显增厚且呈橡胶样，有不规则的区域，从红棕色到淡黄色病灶，类似脂肪坏死，散在分布。显微镜下，纤维脂肪组织的炎症累及显示有圆形细胞、泡沫细胞和巨细胞。摄取了脂肪的巨噬细胞，也称为噬脂细胞，是诊断的标志。文献中已描述了122例肠系膜脂膜炎病例；其中仅3例累及大肠系膜。本文对文献进行了综述，并报告了2例仅累及乙状结肠系膜的新病例。
