Popkharitov Angel I, Chomov Georgi N
Department of Surgery, Thracian University, Medical Faculty, 11 Armeiska str, Stara Zagora 6000, Bulgaria.
J Med Case Rep. 2007 Oct 2;1:108. doi: 10.1186/1752-1947-1-108.
Mesenteric panniculitis of the sigmoid colon is a rare occurrence in surgical practice. The aim of this article is to present a case of mesenteric panniculitis of the sigmoid colon and a short review of the literature.
We reviewed the hospital record of a 63-year-old man who presented with a palpable mass in the left abdomen and clinical signs of a partial bowel obstruction. The pre-operative impression was a possible cancer of the sigmoid colon. A laparotomy was performed through a midline incision. The mesentery was found to be markedly thickened, constricted and puckered. The normal architecture of the adipose tissue had been lost and replaced with an irregular nodular mass. The microscopic pathologic sections demonstrated a chronic reactive inflammatory process with an exuberant proliferation of fibroblasts and fibrocytes. The adipose tissue contained scattered areas of steatonecrosis with foci of lipid-laden macrophages, lymphocytes and plasma cells. The sigmoid colon and its mesocolon were resected. The postoperative course was uneventful and the patient was discharged in good condition, and followed up for the next two years.
Mesenteric panniculitis of sigmoid is an extremely rare entity of unknown origin in which the normal architecture of the mesentery is replaced by fibrosis, necrosis and calcification. On gross examination the alterations may be mistaken for a neoplastic process. A frozen section may be necessary for confirmation of the diagnosis. When the advanced inflammatory changes became irreversible and bowel obstruction occurs, resection may be indicated.
乙状结肠肠系膜脂膜炎在外科实践中较为罕见。本文旨在介绍一例乙状结肠肠系膜脂膜炎病例并对相关文献进行简要综述。
我们回顾了一名63岁男性患者的医院记录,该患者左腹可触及肿块,并伴有部分肠梗阻的临床症状。术前印象为可能是乙状结肠癌。通过中线切口进行了剖腹手术。发现肠系膜明显增厚、收缩和起皱。脂肪组织的正常结构消失,代之以不规则的结节状肿块。显微镜下病理切片显示为慢性反应性炎症过程,伴有成纤维细胞和纤维细胞的过度增生。脂肪组织中有散在的脂肪坏死区域,伴有充满脂质的巨噬细胞、淋巴细胞和浆细胞灶。切除了乙状结肠及其系膜。术后过程顺利,患者康复出院,并在接下来的两年里进行了随访。
乙状结肠肠系膜脂膜炎是一种起源不明的极为罕见的疾病,其中肠系膜的正常结构被纤维化、坏死和钙化所取代。大体检查时,这些改变可能被误诊为肿瘤性病变。可能需要进行冰冻切片以确诊。当炎症进展到不可逆且出现肠梗阻时,可能需要进行切除手术。