部分脾切除术中脾上极与脾下极的大体及显微镜下比较

Macro and microscopic comparison of the upper pole of the spleen with the lower pole in partial splenectomy.

作者信息

Paulo Lucas Nagib Lemos, Alexander Daniel Robert, Vallandro Elisa Ines Demuner, Benevides Raquel de Azevedo, Motta Luciene Lage da, Paulo Marcela Souza Lima, Paulo Danilo Nagib Salomão

机构信息

Graduate student, School of Medicine, Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória (EMESCAM), Vitoria-ES, Brazil. Scientific and intellectual content of the study, technical procedures, manuscript preparation and writing.

Graduate student, School of Medicine, EMESCAM, Vitoria-ES, Brazil. Scientific and intellectual content of the study; technical procedures; acquisition, analysis and interpretation of data.

出版信息

Acta Cir Bras. 2020 Oct 16;35(9):e202000902. doi: 10.1590/s0102-865020200090000002. eCollection 2020.

DOI:10.1590/s0102-865020200090000002

PMID:33084734

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7584296/

Abstract

PURPOSE

To evaluate the viability of the upper (UP) and lower pole (LP) of the spleen from a macro and microscopic point of view, after subtotal splenectomy with preservation (SSP) of the UP and the LP.

METHODS

Seventeen male Wistar rats, two months old, were submitted to SSPUP and SSPLP and 5 to simulated operation (SG). After 80 days, the rats were euthanized, and the remaining LP and UP and intact spleens were evaluated macroscopically and microscopically.

RESULTS

Two rats died during the operation. Macroscopic analysis showed that in 15 LP, one of them was not viable and in 15 UP and in 5 spleens in the SG, all were viable. In the statistical analysis, there was no difference in relation to viability. The LP and UP analyzed showed variation. As for the length, the UP increased significantly; however, in relation to the width, there was a significant increase in the LP in relation to the UP. In addition, the weight of the UP was significantly greater than that of the LP. Microscopic analysis attested viability of the splenic remnants.

CONCLUSION

There was no significant difference regarding the viability of UP and LP, in macroscopy and microscopy.

摘要

目的

从宏观和微观角度评估保留脾脏上极（UP）和下极（LP）的次全脾切除术后，脾脏上极和下极的生存能力。

方法

将17只2月龄雄性Wistar大鼠进行保留脾脏上极的次全脾切除术（SSPUP）和保留脾脏下极的次全脾切除术（SSPLP），5只进行假手术（SG）。80天后，对大鼠实施安乐死，并对剩余的脾脏下极、上极以及完整脾脏进行宏观和微观评估。

结果

2只大鼠在手术过程中死亡。宏观分析显示，在15个脾脏下极中，有1个无生存能力，在15个脾脏上极以及假手术组的5个脾脏中，所有均有生存能力。在统计学分析中，生存能力方面无差异。所分析的脾脏下极和上极存在差异。就长度而言，脾脏上极显著增加；然而，就宽度而言，脾脏下极相对于上极显著增加。此外，脾脏上极的重量显著大于脾脏下极。微观分析证实了脾残余的生存能力。