Department of Ophthalmology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, Turkey.
Arq Bras Oftalmol. 2020 Sep-Oct;83(5):410-416. doi: 10.5935/0004-2749.20200080.
To evaluate the inner retinal and choroidal thicknesses in patients with early retinitis pigmentosa.
We analyzed spectral-domain optical coherence tomography images of 35 retinitis pigmentosa patients and 40 healthy individuals. We measured macular and ganglion cell complex thicknesses. We took choroidal thickness measurements in the subfoveal region and 500, 1,000, and 1,500 mm from the foveal center.
Patients with retinitis pigmentosa had significantly thinner macular thicknesses and choroidal thicknesses in all measurements, and their individual ganglion cell complex thickness measurements were lower than those in healthy individuals. The mean ganglion cell complex thickness was significantly lower in patients with retinitis pigmentosa than that in controls. The mean macular thickness was significantly correlated with the mean choroidal and mean ganglion cell complex thicknesses. (We found no correlation between the mean choroidal thickness and the mean ganglion cell complex thickness).
The choroid was mildly affected in our patients with early retinitis pigmentosa. The tendency toward significance in the inner retina was possibly caused by a good visual acuity.
评估早期视网膜色素变性患者的视网膜内层和脉络膜厚度。
我们分析了 35 例视网膜色素变性患者和 40 名健康个体的光谱域光学相干断层扫描图像。我们测量了黄斑和神经节细胞复合体的厚度。我们在黄斑中心下、距黄斑中心 500、1000 和 1500 处测量脉络膜厚度。
视网膜色素变性患者的黄斑厚度和所有部位的脉络膜厚度均显著变薄，其单个神经节细胞复合体厚度测量值低于健康个体。视网膜色素变性患者的平均神经节细胞复合体厚度明显低于对照组。平均黄斑厚度与平均脉络膜和平均神经节细胞复合体厚度显著相关。（我们发现平均脉络膜厚度与平均神经节细胞复合体厚度之间无相关性）。
我们的早期视网膜色素变性患者的脉络膜受到轻度影响。内层视网膜的趋势可能是由于良好的视力所致。
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