口腔鳞状细胞癌的标准化与个体化诊断及治疗：机遇与挑战
[Standardized and individualized diagnosis and treatment of oral squamous cell carcinoma: opportunities and challenges].
作者信息
Zhong Lai-Ping
机构信息
Dept. of Oral & Maxillofacial-Head & Neck Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200011, China.
出版信息
Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Oct 1;38(5):484-488. doi: 10.7518/hxkq.2020.05.002.
How to improve the effects of treatment on patients with oral squamous cell carcinoma (OSCC) has always been the focus of clinical and basic studies. The standardized diagnosis and treatment of malignant tumors aim to improve the effects of treatment, and individualized treatment based on standardized diagnosis and treatment may further improve these effects. On the basis of the existing guidelines for the diagnosis and treatment of patients with OSCC, this study explored the opportunities and challenges of standardized and individualized diagnosis and treatment of OSCC. These challenges and opportunities were related to the updates of clinical and pathological staging system, surgical margins, and neck dissection in patients with OSCC at early stage and preoperative induction therapy and postoperative adjuvant treatment in patients with advanced OSCC. This study also shared ideas on clinical studies of OSCC to optimize the existing treatment schemes, improve the treatment effects, and enhance the guidelines.
如何提高口腔鳞状细胞癌（OSCC）患者的治疗效果一直是临床和基础研究的重点。恶性肿瘤的规范化诊断和治疗旨在提高治疗效果，基于规范化诊断和治疗的个体化治疗可能会进一步改善这些效果。在现有的OSCC患者诊断和治疗指南的基础上，本研究探讨了OSCC规范化和个体化诊断与治疗的机遇和挑战。这些挑战和机遇与临床和病理分期系统的更新、手术切缘、早期OSCC患者的颈部清扫以及晚期OSCC患者的术前诱导治疗和术后辅助治疗有关。本研究还分享了关于OSCC临床研究的观点，以优化现有治疗方案、提高治疗效果并完善指南。
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