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新诊断的非胰岛素依赖型糖尿病患者的高胰岛素血症与高血压

Hyperinsulinemia and hypertension in patients with newly diagnosed non-insulin-dependent diabetes.

作者信息

Uusitupa M, Niskanen L, Siitonen O, Pyörälä K

机构信息

Department of Medicine, University of Kuopio, Finland.

出版信息

Diabete Metab. 1987 Jul;13(3 Pt 2):369-74.

PMID:3308567
Abstract

An increased occurrence of hypertension was observed in a group of patients (N = 133) with newly diagnosed non-insulin-dependent diabetes as compared to non-diabetic control subjects (N = 144). In men the excessive occurrence of hypertension in diabetics seemed to be mainly confined to obese subjects, whereas in women it occurred both in obese and non-obese subjects. Fasting or postglucose serum insulin levels showed a positive correlation with blood pressure levels in non-diabetic men and in diabetic and non-diabetic women even after adjustment of insulin for obesity.

摘要

与非糖尿病对照受试者(N = 144)相比,在一组新诊断为非胰岛素依赖型糖尿病的患者(N = 133)中观察到高血压发生率增加。在男性中,糖尿病患者高血压的过多发生似乎主要局限于肥胖受试者,而在女性中,肥胖和非肥胖受试者均有发生。即使在对肥胖进行胰岛素校正后,空腹或葡萄糖后血清胰岛素水平在非糖尿病男性以及糖尿病和非糖尿病女性中均与血压水平呈正相关。

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Hyperinsulinemia and hypertension in patients with newly diagnosed non-insulin-dependent diabetes.新诊断的非胰岛素依赖型糖尿病患者的高胰岛素血症与高血压
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