Ravindran Roshini, Kwok Chun Shing, Wong Chun Wai, Siller-Matula Jolanta M, Parwani Purvi, Velagapudi Poonam, Fischman David L, Alraies Chadi, Michos Erin D, Mamas Mamas A
Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK; Royal Stoke University Hospital, Stoke-on-Trent, UK.
Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, UK; Royal Stoke University Hospital, Stoke-on-Trent, UK.
Resuscitation. 2020 Dec;157:166-173. doi: 10.1016/j.resuscitation.2020.10.005. Epub 2020 Oct 19.
The aim of this study is to analyse the causes of cardiac arrests (CA) in the emergency departments (ED) in the United States and their clinical outcomes according to whether they had a primary or a secondary diagnosis of CA.
Data from the Nationwide Emergency Department Sample was assessed for episodes of CA in the emergency department (ED) for adults from 2006 to 2014. Primary and secondary diagnoses of CA and mortality outcomes were evaluated in ED, inpatient and the combined in-hospital setting.
There were 2,852,347 ED episodes with a diagnosis of CA (50.5% primary diagnosis, 49.5% secondary diagnosis). Among patients with a secondary diagnosis of CA, ∼33% patients had a primary cardiac diagnosis, followed by infectious and respiratory diagnoses. The survival to ED discharge was 53.2%; lower for primary versus secondary CA diagnosis (20.4% vs 86.7%). The in-hospital survival rate for all CA was 28.7%, and was lower for primary versus secondary CA diagnosis (15.7% vs 41.9%). Survival to hospital discharge was highest in the age group of 41-60 years (33.0%) and was least among >80 years (20.9%). Survival was also noted to be lower among female patients (27.9% vs 29.2%) and in the winter months.
Survival with CA in ED is <30% of patients and is greater among patients with a secondary diagnosis of CA. CAs are associated with significant mortality in ED and hospital settings and measures should be taken to better manage cardiac, infection and respiratory causes particularly in the winter months.
本研究旨在分析美国急诊科心脏骤停(CA)的病因及其临床结局,并根据CA的主要诊断或次要诊断进行分类。
评估2006年至2014年美国全国急诊科样本中成人急诊科CA发作的数据。在急诊科、住院部和综合医院环境中评估CA的主要和次要诊断以及死亡率结局。
有2,852,347例急诊科发作被诊断为CA(50.5%为主要诊断,49.5%为次要诊断)。在CA次要诊断的患者中,约33%的患者主要诊断为心脏疾病,其次是感染性和呼吸道疾病诊断。急诊科出院生存率为53.2%;主要CA诊断患者的生存率低于次要CA诊断患者(20.4%对86.7%)。所有CA患者的院内生存率为28.7%,主要CA诊断患者的生存率低于次要CA诊断患者(15.7%对41.9%)。41-60岁年龄组的出院生存率最高(33.0%),80岁以上患者的出院生存率最低(20.9%)。女性患者的生存率也较低(27.9%对29.2%),且在冬季月份生存率更低。
急诊科CA患者的生存率<30%,次要诊断为CA的患者生存率更高。CA在急诊科和医院环境中与显著的死亡率相关,应采取措施更好地管理心脏、感染和呼吸道病因,特别是在冬季月份。