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患者在腔内泌尿外科手术过程中的辐射暴露:IAEA-SEGUR 研究。

Radiation exposure of patients during endourological procedures: IAEA-SEGUR study.

机构信息

Radiation Protection of Patients Unit, International Atomic Energy Agency, Vienna, Austria.

Second Nuclear Medicine Department, Acibadem City Clinic UMHAT, Sofia, Bulgaria.

出版信息

J Radiol Prot. 2020 Nov 20;40(4). doi: 10.1088/1361-6498/abc351.

Abstract

Fluoroscopy is increasingly used to guide minimally invasive endourological procedures and optimised protocols are needed to minimise radiation exposure while achieving best treatment results. This multi-center study of radiation exposure of patients was conducted by the South-Eastern European Group for Urolithiasis Research (SEGUR), in cooperation with the International Atomic Energy Agency. Seven clinical centers from the SEGUR group collected data for 325 procedures performed within a three-months period, including standard percutaneous nephrolithotomy (PCNL), mini PCNL, retrograde intrarenal surgery (RIRS), semirigid ureterorenoscopy (URS) and flexible URS. Data included: air kerma area product (), air kerma at the patient entrance reference point (), fluoroscopy time (FT), number of radiographic images () and fluoroscopy pulse rate, as well as total procedure duration, size and location of stones. Data were centrally analysed and statistically compared. Medianvalues per center varied 2-fold for RIRS (0.80-1.79 Gy cm), 7.1 fold for mini-PCNL (1.39-9.90 Gy cm), 7.3 fold for PCNL (2.40-17.50 Gy cm), 19 fold (0.13-2.51 Gy cm) for semi-rigid URS and 29-fold for flexible URS (0.10-2.90 Gy cm). Lowerandwere associated with use of lower FT,and lower fluoroscopy pulse rate. FT varied from 0.1 to 14 min, a small fraction of the total procedure time, ranging from 10 to 225 min. Higherwas associated with higherand. Higher medianin PCNL was associated with the use of supine compared to prone position. No correlation was found between the concrement size and procedure duration, FT,or. Dose values for RIRS were significantly lower compared to PCNL. The maximumvalue of 377 mGy was under the threshold for radiation induced skin erythema. The study demonstrated a potential for patient dose reduction by lowering FT and, using pulsed fluoroscopy and beam collimation.

摘要

荧光透视术越来越多地用于指导微创内镜手术,需要制定最佳的方案来减少辐射暴露,同时获得最佳的治疗效果。这项针对患者辐射暴露的多中心研究由东南欧尿路结石研究组(SEGUR)与国际原子能机构合作开展。SEGUR 组的七个临床中心在三个月的时间内收集了 325 例手术的数据,包括标准经皮肾镜碎石取石术(PCNL)、微型 PCNL、逆行性肾内手术(RIRS)、半刚性输尿管镜检查(URS)和软性输尿管镜检查(URS)。数据包括:空气比释动能面积乘积()、患者入射参考点处的空气比释动能()、荧光透视时间(FT)、放射影像数量()和荧光透视脉冲率,以及总手术时间、结石的大小和位置。数据经中心分析并进行统计学比较。每个中心的中位数差异 RIRS 为 2 倍(0.80-1.79 Gy cm)、微型 PCNL 为 7.1 倍(1.39-9.90 Gy cm)、PCNL 为 7.3 倍(2.40-17.50 Gy cm)、半刚性 URS 为 19 倍(0.13-2.51 Gy cm),软性 URS 为 29 倍(0.10-2.90 Gy cm)。较低的和与较低的 FT 和较低的荧光透视脉冲率相关。FT 从 0.1 到 14 分钟不等,占总手术时间的一小部分,范围从 10 到 225 分钟。较高的与较高的和相关。PCNL 中较高的中位数与仰卧位与俯卧位的使用相关。结石大小与手术时间、FT 或之间没有相关性。RIRS 的剂量值明显低于 PCNL。最大 377 mGy 的值低于辐射引起皮肤红斑的阈值。该研究表明,通过降低 FT 并使用脉冲荧光透视术和束准直,可以降低患者的剂量。

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