Pediatrics. 2021 Jan;147(Suppl 1). doi: 10.1542/peds.2020-038505C. Epub 2020 Oct 21.
This (CoSTR) for neonatal life support includes evidence from 7 systematic reviews, 3 scoping reviews, and 12 evidence updates. The Neonatal Life Support Task Force generally determined by consensus the type of evidence evaluation to perform; the topics for the evidence updates followed consultation with International Liaison Committee on Resuscitation member resuscitation councils. The 2020 CoSTRs for neonatal life support are published either as new statements or, if appropriate, reiterations of existing statements when the task force found they remained valid.Evidence review topics of particular interest include the use of suction in the presence of both clear and meconium-stained amniotic fluid, sustained inflations for initiation of positive-pressure ventilation, initial oxygen concentrations for initiation of resuscitation in both preterm and term infants, use of epinephrine (adrenaline) when ventilation and compressions fail to stabilize the newborn infant, appropriate routes of drug delivery during resuscitation, and consideration of when it is appropriate to redirect resuscitation efforts after significant efforts have failed.All sections of the Neonatal Resuscitation Algorithm are addressed, from preparation through to postresuscitation care. This document now forms the basis for ongoing evidence evaluation and reevaluation, which will be triggered as further evidence is published.Over 140 million babies are born annually worldwide (https://ourworldindata.org/grapher/births-and-deaths-projected-to-2100). If up to 5% receive positive-pressure ventilation, this evidence evaluation is relevant to more than 7 million newborn infants every year. However, in terms of early care of the newborn infant, some of the topics addressed are relevant to every single baby born.
这份新生儿生命支持指南(CoSTR)包括来自 7 项系统评价、3 项范围评价和 12 项证据更新的证据。新生儿生命支持特别工作组通常通过共识确定要进行的证据评估类型;证据更新的主题是在与国际复苏联络委员会成员复苏理事会协商后确定的。2020 年新生儿生命支持 CoSTR 要么作为新的声明发布,要么在特别工作组发现它们仍然有效的情况下,重复现有的声明。特别感兴趣的证据审查主题包括在羊水清晰和胎粪污染时使用吸引、持续充气以启动正压通气、开始复苏时的初始氧浓度在早产儿和足月儿中、在通气和按压未能稳定新生儿时使用肾上腺素(肾上腺素)、复苏期间适当的药物给药途径,以及考虑在经过大量努力后何时适当地重新调整复苏努力。新生儿复苏算法的所有部分都得到了处理,从准备到复苏后护理。本文件现在是正在进行的证据评估和重新评估的基础,随着更多证据的发布,将触发这些评估。全世界每年有超过 1.4 亿婴儿出生(https://ourworldindata.org/grapher/births-and-deaths-projected-to-2100)。如果多达 5%的婴儿接受正压通气,那么每年有超过 700 万新生儿需要进行这项证据评估。然而,就新生儿的早期护理而言,所涉及的一些主题与每个出生的婴儿都有关。