Park Joon Yeun, Lee Yu Hyun
Department of Nuclear Medicine, Myongji Hospital, Goyang-si, Gyeonggi-do Republic of Korea.
Department of Radiology, Myongji Hospital, Goyang-si, Gyeonggi-do Republic of Korea.
Nucl Med Mol Imaging. 2020 Oct;54(5):252-255. doi: 10.1007/s13139-020-00658-3. Epub 2020 Jul 25.
Cervical metastasis of squamous cell carcinoma from an unknown primary site occurs in approximately 2-4% of head and neck tumor cases. Without identification of the primary site, proper management cannot be achieved, resulting in significant morbidity and a lower cure rate. For the primary site assessment, positron emission tomography/computed tomography (PET/CT) using the radiotracer F-fluorodeoxyglucose (FDG) is the imaging modality of choice and has been shown to be superior to CT alone. Here, we report a case of cervical metastasis of squamous cell carcinoma in an 82-year-old man. F-FDG PET/CT revealed a tongue-base lesion, although neck CT detected no lesions because of artifacts from dental prosthesis, which was suspected as the primary site. The final diagnosis was confirmed as tongue-base cancer with neck lymph node metastases through biopsy. These results suggest that F-FDG PET/CT is a valuable diagnostic tool in patients with cervical metastatic lymph nodes because it can demonstrate primary tumors in patients with dental prosthesis.
原发部位不明的鳞状细胞癌发生颈部转移约占头颈部肿瘤病例的2 - 4%。若未明确原发部位，就无法实现恰当的治疗，从而导致显著的发病率和较低的治愈率。对于原发部位评估，使用放射性示踪剂F - 氟脱氧葡萄糖（FDG）的正电子发射断层扫描/计算机断层扫描（PET/CT）是首选的成像方式，且已证明其优于单纯的CT。在此，我们报告一例82岁男性鳞状细胞癌颈部转移的病例。F - FDG PET/CT显示了舌根处的病变，尽管颈部CT因假牙伪影未检测到病变，该病变被怀疑为原发部位。最终诊断通过活检确认为舌根癌伴颈部淋巴结转移。这些结果表明，F - FDG PET/CT对于颈部转移性淋巴结患者是一种有价值的诊断工具，因为它能够显示有假牙患者的原发肿瘤。
