Misirlioglu Merve, Yildizdas Dincer, Ekinci Faruk, Horoz Ozden Ozgur, Yontem Ahmet
Department of Pediatric Intensive Care, Cukurova University Faculty of Medicine, Adana, Turkey.
Turk J Emerg Med. 2020 Oct 7;20(4):199-201. doi: 10.4103/2452-2473.297465. eCollection 2020 Oct-Dec.
Acute pancreatitis is a reversible inflammatory condition of the pancreas. It usually develops on the basis of trauma, structural abnormalities, and chronic systemic diseases. A definitive causal correlation between a drug and acute pancreatitis is quite difficult for clinicians. Drugs play a vital role in the etiology in approximately 10% of children with pancreatitis. More than 50 drugs including angiotensin-converting enzyme inhibitors have been reported to cause pancreatic damage. There was no pediatric case report developed pancreatitis following perindopril use. A pediatric case of pancreatitis following perindopril intake was presented in this article to emphasize pancreatitis, which is one of the complications that may occur after drug intake.
急性胰腺炎是胰腺的一种可逆性炎症性疾病。它通常在创伤、结构异常和慢性全身性疾病的基础上发展而来。对于临床医生来说，确定药物与急性胰腺炎之间明确的因果关系相当困难。在约10%的儿童胰腺炎病因中，药物起着至关重要的作用。据报道，包括血管紧张素转换酶抑制剂在内的50多种药物可导致胰腺损伤。此前没有关于培哚普利使用后发生胰腺炎的儿科病例报告。本文介绍了一例因服用培哚普利后发生胰腺炎的儿科病例，以强调胰腺炎是药物摄入后可能发生的并发症之一。
