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利用南卡罗来纳州的 STOP-BAG 问卷对阻塞性睡眠呼吸暂停的医疗负担进行基于人群的估计。

A population-based estimate of the health care burden of obstructive sleep apnea using a STOP-BAG questionnaire in South Carolina.

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.

South Carolina Department of Health and Environmental Control, Columbia, South Carolina.

出版信息

J Clin Sleep Med. 2021 Mar 1;17(3):367-374. doi: 10.5664/jcsm.8860.

DOI:10.5664/jcsm.8860
PMID:33089773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7927332/
Abstract

STUDY OBJECTIVES

Population based estimates of obstructive sleep apnea (OSA) frequency and health impact are incomplete. The aim of this study was to determine the prevalence of risk factors for physician and sleep study diagnosed OSA among individuals in a state-based surveillance program.

METHODS

Using questions inserted into the 2016 (n = 5,564) and 2017 (n = 10,884) South Carolina Behavioral Risk Factor Surveillance System of the Centers for Disease Control and Prevention, we analyzed the prevalence of physician diagnosed OSA and associated comorbidities. The validated STOP-BANG questionnaire without neck circumference (STOP-BAG) defined populations at moderate risk (score 3-4) and high risk (score 5-7). Statistical analysis using weighted prevalence and means and their 95% confidence intervals (CI) thus reflect population estimates of disease burden.

RESULTS

The population-based prevalence of physician diagnosed OSA in South Carolina was 9.7% (95% CI: 9.0-10.4). However, the populations with moderate risk (18.5%, 95% CI: 17.3-19.8) and high risk (25.5%, 95% CI: 23.9-27.1) for OSA, as determined by the STOP-BAG questionnaire, were much higher. Compared to those at low risk for OSA, those at high risk were more often diagnosed with coronary heart disease, stroke, asthma, skin cancer, other cancers, chronic obstructive pulmonary disease, arthritis, depression, kidney disease, and diabetes (all P < .001).

CONCLUSIONS

OSA is common and strongly associated with major comorbidities. As such, this public health crisis warrants more diagnostic and therapeutic attention. The STOP-BAG questionnaire provides a public health platform to monitor this disease.

摘要

研究目的

基于人群的阻塞性睡眠呼吸暂停(OSA)频率和健康影响的估计并不完整。本研究的目的是确定在州级监测计划中,医生和睡眠研究诊断的 OSA 风险因素在个体中的流行率。

方法

使用插入疾病控制和预防中心 2016 年(n=5564)和 2017 年(n=10884)南卡罗来纳州行为风险因素监测系统的问题,我们分析了医生诊断的 OSA 及其相关合并症的流行率。不包括颈围的验证 STOP-BANG 问卷(STOP-BAG)将人群定义为中度风险(评分 3-4)和高风险(评分 5-7)。使用加权流行率和平均值及其 95%置信区间(CI)进行统计分析,从而反映疾病负担的人群估计。

结果

南卡罗来纳州医生诊断的 OSA 的人群流行率为 9.7%(95%CI:9.0-10.4)。然而,根据 STOP-BAG 问卷确定的中度风险(18.5%,95%CI:17.3-19.8)和高风险(25.5%,95%CI:23.9-27.1)人群的 OSA 风险要高得多。与 OSA 低风险人群相比,高风险人群更常被诊断为冠心病、中风、哮喘、皮肤癌、其他癌症、慢性阻塞性肺疾病、关节炎、抑郁症、肾病和糖尿病(均 P<.001)。

结论

OSA 很常见,并且与主要合并症密切相关。因此,这种公共卫生危机需要更多的诊断和治疗关注。STOP-BAG 问卷为监测这种疾病提供了一个公共卫生平台。