水痘-带状疱疹病毒感染后格林-巴利综合征。两例报告。
Guillain-Barré syndrome after varicella-zoster infection. Report of two cases.
作者信息
Sanders E A, Peters A C, Gratana J W, Hughes R A
机构信息
Department of Neurology, United Medical School, Guy's Hospital, London, England.
出版信息
J Neurol. 1987 Aug;234(6):437-9. doi: 10.1007/BF00314094.
Two patients developed Guillain-Barré syndrome after varicella-zoster infection; a 4-year-old boy after chickenpox and a 74-year-old man after shingles. Both had decreased CD8-positive lymphocytes in the blood during the course of their illness. These cases and others reported in the literature suggest that varicella-zoster infection is a significant but rare trigger factor of Guillain-Barré syndrome. An alteration in the balance of helper and suppressor lymphocytes may be an important pathogenetic mechanism.
两名患者在水痘-带状疱疹感染后患上格林-巴利综合征；一名4岁男孩在患水痘后发病，一名74岁男子在患带状疱疹后发病。两名患者在病程中血液中的CD8阳性淋巴细胞均减少。这些病例以及文献中报道的其他病例表明，水痘-带状疱疹感染是格林-巴利综合征的一个重要但罕见的触发因素。辅助性淋巴细胞和抑制性淋巴细胞平衡的改变可能是一个重要的发病机制。
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