Multidisciplinary Department of Medical-Surgical and Dental Specialties, Luigi Vanvitelli University of Campania, Naples, Italy.
Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy.
Minerva Dent Oral Sci. 2021 Feb;70(1):26-31. doi: 10.23736/S2724-6329.20.04422-2. Epub 2020 Oct 23.
Odontogenic keratocyst (OKC) can be classified as an oral lesion representing the third most common cyst of the jaws characterized by a high rate of recurrence. OKC was accepted as a neoplastic lesion in the 2005 WHO classification and it was called keratocystic odontogenic tumor (KCOT). However, in the 2017 classification of odontogenic tumors, OKC was moved back into the cyst category. This study aimed to evaluate clinically, radiographically and through the histological examination, the healing of a patient with OKC who underwent surgery with a marsupialization approach.
A 83-year-old female patient, presented deformation of the right hemi-mandibular region and paresthesia of the right hemi-labium. During intraoral examination it was possible to detect an eggshell crackle on palpation of the anterior edentulous mandible; moreover, the patient reported a growth of the lesion over time that prevented her from using the removable prosthesis. At the OPT it was possible to appreciate a unilocular area that extended from the parasymphyseal region to the right hemi-mandible. The CT scan showed massive erosion that only partially spared the lower cortex and involvement of the mental foramen.
Checks following surgery show healing also confirmed by instrumental check-ups.
Surely this study offers a valid alternative to more invasive and debilitating surgical treatments.
牙源性角化囊肿（OKC）可归类为口腔病变，是颌骨第三常见的囊肿，其复发率较高。OKC 在 2005 年的 WHO 分类中被认为是一种肿瘤性病变，被称为角化囊性牙源性肿瘤（KCOT）。然而，在 2017 年的牙源性肿瘤分类中，OKC 被归回到囊肿类别。本研究旨在通过临床、影像学和组织学检查评估一位接受袋形手术治疗 OKC 患者的愈合情况。
一位 83 岁女性患者，表现为右下颌半区变形和右侧半唇麻木。口腔检查时，在前磨牙无牙区触诊可发现蛋壳样爆裂声；此外，患者报告说病变随着时间的推移而生长，导致她无法使用可摘义齿。在 OPT 中可以看到一个从正中联合区域延伸到右侧下颌骨的单房区域。CT 扫描显示广泛的侵蚀，仅部分保留了下皮质，并累及颏孔。
手术后的检查显示愈合良好，仪器检查也证实了这一点。
这项研究无疑为更具侵袭性和致残性的手术治疗提供了一种有效的替代方案。
