Jaeger Filipe, de Noronha Mariana Saturnino, Silva Maiza Luiza Vieira, Amaral Márcio Bruno Figueiredo, Grossmann Soraya de Mattos Carmago, Horta Martinho Campolina Rebello, de Souza Paulo Eduardo Alencar, de Aguiar Maria Cássia Ferreira, Mesquita Ricardo Alves
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Department of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, Brazil; Department of Dentistry, Centro Universitário Newton Paiva, Belo Horizonte, Brazil.
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
J Craniomaxillofac Surg. 2017 Feb;45(2):267-270. doi: 10.1016/j.jcms.2016.12.011. Epub 2016 Dec 18.
The aim of this study was to evaluate the impact of the reclassification of odontogenic keratocyst (OKC) as a tumor on the prevalence profile of odontogenic cysts (OCs) and odontogenic tumors (OTs).
Two referral Oral and Maxillofacial Pathology services in Brazil were evaluated. All cases diagnosed as OCs or OTs were selected and classified according to the 1992 WHO-classification (cases before 2005 WHO classification of tumors excluding OKC) and the 2005 WHO classification of tumors, going forward including cases of odontogenic keratocyst tumor (KCOT). The frequency and prevalence of OCs and OTs were compared before and after the reclassification.
Among 27,854 oral biopsies, 4920 (17.66%) were OCs and 992 (3.56%) were OTs. The prevalence of OTs before 2005 WHO classification of tumors was 2.04%, while the prevalence after 2005 WHO classification was 11.51% (p < 0.0001). Before 2006, the most frequent tumor diagnosed was odontoma with 194 cases (39.67%), and after 2005 WHO classification of tumors the KCOT was the most frequent with 207 cases (41.07%).
The increase in the prevalence of OTs after 2005 WHO is related to the improvement of pathology services and to the inclusion of KCOT in the OTs group.
本研究旨在评估将牙源性角化囊肿（OKC）重新分类为肿瘤对牙源性囊肿（OCs）和牙源性肿瘤（OTs）患病率的影响。
对巴西两家转诊的口腔颌面病理学服务机构进行评估。选择所有诊断为OCs或OTs的病例，并根据1992年世界卫生组织分类（2005年世界卫生组织肿瘤分类之前的病例，不包括OKC）和2005年世界卫生组织肿瘤分类进行分类，此后包括牙源性角化囊肿性肿瘤（KCOT）病例。比较重新分类前后OCs和OTs的频率和患病率。
在27854例口腔活检中，4920例（17.66%）为OCs，992例（3.56%）为OTs。2005年世界卫生组织肿瘤分类之前OTs的患病率为2.04%，而2005年世界卫生组织分类之后的患病率为11.51%（p<0.0001）。2006年之前，诊断出的最常见肿瘤是牙瘤，有194例（39.67%），2005年世界卫生组织肿瘤分类之后，KCOT最常见，有207例（41.07%）。
2005年世界卫生组织分类之后OTs患病率的增加与病理服务的改善以及KCOT纳入OTs组有关。
