de Souza Sittart J A, Sakai Valente N Y
Hospital do Servidor Publico do Estado de São Paulo, Brasil.
Med Cutan Ibero Lat Am. 1987;15(2):151-6.
37 keloid patients were treated with triamcinolone intralesionally every 15 days, in all 6 inoculations. Histologically after the treatment we observed alterations in dermal vascularization, in morphology, in color characteristics and in the arrangement of the collagen bundles. The disappearance of mucin and the presence of palisade granulomas was observed in some cases probably because of the corticoid deposited. There was regression of pruritus and pain in all the patients. We believe that the intralesionally infiltration of corticoid is even today one of the best methods of treatment, and it may also be effected together with other technics.
37名瘢痕疙瘩患者每隔15天接受一次曲安奈德皮损内注射，共注射6次。治疗后组织学观察发现，真皮血管化、形态、颜色特征及胶原束排列均有改变。部分病例可见黏蛋白消失及栅栏状肉芽肿形成，可能是由于皮质类固醇沉积所致。所有患者的瘙痒和疼痛均有缓解。我们认为，即使在今天，皮损内注射皮质类固醇仍是最佳治疗方法之一，也可与其他技术联合使用。
