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运用路径分析方法阐明精神分裂症患者的内化污名、认知洞察力、疾病严重程度和功能之间的关系。

Elucidating the relationship between internalized stigma, cognitive insight, illness severity, and functioning in patients with schizophrenia using a path analysis approach.

机构信息

Department of Psychiatry, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.

The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong SAR, China.

出版信息

J Ment Health. 2022 Feb;31(1):29-38. doi: 10.1080/09638237.2020.1836553. Epub 2020 Oct 23.

DOI:10.1080/09638237.2020.1836553
PMID:33095070
Abstract

BACKGROUND

There is a paucity of studies examining the interrelationship between internalized stigma, cognitive insight, illness severity, and functioning.

AIMS

This study examined the dynamics of the relationship between these factors using a path modelling approach.

METHODS

Two hundred and seven patients with schizophrenia spectrum disorders were recruited in this cross-sectional study. Patients were assessed on internalized stigma, cognitive insight (including its two domains, self-reflectiveness and self-certainty), illness severity and functioning. Path analysis was used to test the hypothesized model for the interrelationship between the variables.

RESULTS

A direct positive association was observed between self-certainty and internalized stigma. This was also observed via the paths running through illness severity and functioning. Self-reflectiveness was only associated with self-certainty in the model. The residual variance of internalized stigma in the path model was relatively high.

CONCLUSION

Our findings highlight that self-certainty is associated with internalized stigma along with illness severity and functioning in individuals with schizophrenia. Therefore, interventions on reduction of internalized stigma may benefit from a multipronged approach targeting self-certainty, illness severity and functioning. The relatively high residual variance of internalized stigma in the model highlights the need for further research to provide better understanding on the mechanisms underlying internalized stigma.

摘要

背景

目前,研究内部污名化、认知洞察、疾病严重程度和功能之间相互关系的研究较少。

目的

本研究采用路径建模方法来检验这些因素之间关系的动态变化。

方法

本横断面研究共招募了 207 名精神分裂症谱系障碍患者。对患者进行内部污名化、认知洞察力(包括自我反思和自我确信两个维度)、疾病严重程度和功能评估。路径分析用于检验变量之间相互关系的假设模型。

结果

自我确信与内部污名化之间存在直接的正相关关系。这种关系也可以通过疾病严重程度和功能的路径来观察。自我反思仅在模型中与自我确信相关。路径模型中内部污名化的残差方差相对较高。

结论

我们的研究结果表明,在精神分裂症患者中,自我确信与内部污名化以及疾病严重程度和功能有关。因此,减少内部污名化的干预措施可能需要采取多管齐下的方法,针对自我确信、疾病严重程度和功能。模型中内部污名化的残差方差相对较高,这表明需要进一步研究,以更好地了解内部污名化的潜在机制。

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