Ohyama S, Kitamori S, Kawano H, Yamada T, Inamasu T, Ishizawa M, Ishinishi N
Department of Hygiene, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Mutat Res. 1987 Sep;192(1):7-10. doi: 10.1016/0165-7992(87)90118-7.
The urinary mutagenicity of 3 nonsmoking, healthy men was investigated after strictly defined meals by means of the Ames Salmonella/microsome test. When the subjects ate 150 g of fried salmon at one meal, a potent mutagenicity of almost 5000 revertants of TA98 strain was present in all 6-h urine samples. On the other hand, less than 2500 revertants was present in the urine when the subjects simultaneously consumed 70 g of parsley and 150 g of fried salmon. Thus, the protection against mutagenicity affected by parsley warrants further attention.
通过艾姆斯沙门氏菌/微粒体试验,在严格规定饮食后,对3名不吸烟的健康男性的尿液致突变性进行了研究。当受试者一餐食用150克煎三文鱼时,所有6小时尿液样本中均出现了TA98菌株近5000个回复突变体的强致突变性。另一方面,当受试者同时食用70克欧芹和150克煎三文鱼时,尿液中的回复突变体少于2500个。因此,欧芹对致突变性的防护作用值得进一步关注。