Department of Surgery, Chungnam National University Hospital, 282, Munhwa-ro, Jung-gu, Daejeon, 35015, Republic of Korea.
Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea.
Surg Oncol. 2020 Dec;35:475. doi: 10.1016/j.suronc.2020.10.006. Epub 2020 Oct 16.
Laparoscopic reoperation of postoperatively diagnosed gallbladder cancer is a technically challenging procedure due to inflammatory adhesion or fibrosis around the hepatoduodenal ligament and gallbladder bed [1,2]. Here we describe a technique for laparoscopic bile duct resection with lymph node dissection in a patient with cystic duct cancer diagnosed after laparoscopic cholecystectomy.
A 73-year-old woman presented with postoperatively diagnosed gallbladder cancer. She underwent laparoscopic cholecystectomy to treat symptomatic gallbladder stones at another hospital, 2 months earlier. Postoperative pathology revealed a 0.9 × 0.7 cm, T2 lesion of adenosquamous carcinoma located at the cystic duct. The cystic duct margin showed high-grade dysplasia. We planned to perform laparoscopic bile duct resection with lymph node dissection. After adhesiolysis to expose the hepatoduodenal ligament, the lymph nodes were dissected around the retropancreatic area, hepatoduodenal ligament, and common hepatic artery in an en bloc fashion. Combined segmental resection of the bile duct, including the fibrotic scar around the cystic duct stump, was completed with negative resection margins. Retrocolic choledochojejunostomy and side-to-side jejunojejunostomy were then performed intracorporeally.
The operation time was 195 minutes and the estimated intraoperative blood loss was minimal. The postoperative pathologic report revealed no residual tumor tissue and negative resection margins. Lymph node metastasis was found in one of eight retrieved lymph nodes. The patient was discharged on postoperative day 4 with no postoperative complications.
Laparoscopic radical surgery involving bile duct resection and lymph node dissection can be safely performed in patients with postoperatively diagnosed gallbladder cancer.
由于肝十二指肠韧带和胆囊床周围的炎症粘连或纤维化,术后诊断为胆囊癌的腹腔镜再次手术是一项技术挑战性的操作[1,2]。在这里,我们描述了一种在腹腔镜胆囊切除术后诊断为胆囊管癌的患者中行腹腔镜胆管切除和淋巴结清扫的技术。
一名 73 岁女性因术后诊断为胆囊癌就诊。她 2 个月前在另一家医院因症状性胆囊结石行腹腔镜胆囊切除术。术后病理显示,位于胆囊管的 0.9×0.7 cm、T2 级腺鳞癌,胆囊管切缘显示高级别异型增生。我们计划行腹腔镜胆管切除和淋巴结清扫。在松解粘连以暴露肝十二指肠韧带后,整块地在胰后区域、肝十二指肠韧带和肝总动脉周围解剖淋巴结。联合切除包括胆囊管残端纤维瘢痕在内的胆管节段,切缘阴性。然后行结肠后胆肠吻合和侧侧空肠空肠吻合。
手术时间为 195 分钟,术中估计出血量极少。术后病理报告显示无残留肿瘤组织和切缘阴性。在 8 个送检淋巴结中发现 1 个淋巴结有转移。患者术后第 4 天无术后并发症出院。
对于术后诊断为胆囊癌的患者,行包括胆管切除和淋巴结清扫的腹腔镜根治性手术是安全可行的。