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腹腔镜辅助下根治性胆囊切除术治疗 T2 期胆囊癌。

Laparoscopic completion radical cholecystectomy for T2 gallbladder cancer.

机构信息

Department of Surgical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue C-308, Philadelphia, PA 19111, USA.

出版信息

Surg Endosc. 2010 Dec;24(12):3221-3. doi: 10.1007/s00464-010-1102-2. Epub 2010 May 25.

Abstract

BACKGROUND

The role of minimally invasive surgery in the surgical management of gallbladder cancer is a matter of controversy. Because of the authors' growing experience with laparoscopic liver and pancreatic surgery, they have begun offering patients laparoscopic completion partial hepatectomies of the gallbladder bed with laparoscopic hepatoduodenal lymphadenectomy.

METHODS

The video shows the steps needed to perform laparoscopic resection of the residual gallbladder bed, the hepatoduodenal lymph node nodes, and the residual cystic duct stump in a setting with a positive cystic stump margin. The skin and fascia around the previous extraction site are resected, and this site is used for specimen retrieval during the second operation.

RESULTS

To date, three patients have undergone laparoscopic radical cholecystectomy with hepatoduodenal lymph node dissection for gallbladder cancer. The average number of lymph nodes retrieved was 3 (range, 1-6), and the average estimated blood loss was 117 ml (range, 50-200 ml). The average operative time was 227 min (range, 120-360 min), and the average hospital length of stay was 4 days (range, 3-5 days). No morbidity or mortality was observed during 90 days of follow-up for each patient.

CONCLUSION

Although controversy exists as to the best surgical approach for gallbladder cancer diagnosed after routine laparoscopic cholecystectomy, the minimally invasive approach seems feasible and safe, even after previous hepatobiliary surgery. If the previous extraction site cannot be ascertained, all port sites can be excised locally. Larger studies are needed to determine whether the minimally invasive approach to postoperatively diagnosed early-stage gallbladder cancer has any drawbacks.

摘要

背景

微创外科在胆囊癌手术治疗中的作用仍存在争议。由于作者在腹腔镜肝、胰腺手术方面的经验不断增加,他们开始为患者提供腹腔镜下完成胆囊床部分肝切除术和腹腔镜下肝十二指肠淋巴结清扫术。

方法

该视频展示了在胆囊残端阳性边界的情况下,行腹腔镜下切除残余胆囊床、肝十二指肠淋巴结和残余胆囊管残端所需的步骤。切除原切口周围的皮肤和筋膜,此部位可用于第二次手术时取标本。

结果

迄今为止,有 3 例胆囊癌患者行腹腔镜根治性胆囊切除术和肝十二指肠淋巴结清扫术。平均取淋巴结数为 3 枚(范围 1-6 枚),平均估计出血量为 117ml(范围 50-200ml)。平均手术时间为 227 分钟(范围 120-360 分钟),平均住院时间为 4 天(范围 3-5 天)。每位患者随访 90 天内均未观察到发病率或死亡率。

结论

虽然对于常规腹腔镜胆囊切除术后诊断的胆囊癌的最佳手术方法存在争议,但微创方法似乎是可行且安全的,即使在先前的肝胆手术之后也是如此。如果无法确定原切口位置,可以局部切除所有的端口部位。需要更大的研究来确定微创方法治疗术后诊断的早期胆囊癌是否有任何缺点。

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