Tommaso Morena Di, Miglio Arianna, Crisi Paolo Emidio, Boari Andrea, Rocconi Francesca, Antognoni Maria Teresa, Luciani Alessia
Faculty of Veterinary Medicine, Veterinary University Hospital, University of Teramo, Piano d'Accio, 64100 Teramo, Italy.
Department of Veterinary Medicine, University of Perugia, 06100 Perugia, Italy.
Animals (Basel). 2020 Oct 21;10(10):1937. doi: 10.3390/ani10101937.
Blood transfusion reactions and neonatal isoerythrolysis are common events in the feline population due to the presence of natural alloantibodies in the AB blood group system. It is known that the frequency of feline blood types varies according to the geographic region and breed. Therefore, the aims of this study were to investigate the frequency of AB blood groups in non-pedigree domestic cats in Central Italy and estimate the risk of a life-threatening transfusion reaction and neonatal isoerythrolysis, caused by mismatched transfusion or incompatible random mating, respectively. The AB blood group was determined on non-pedigree domestic feline patients and potential blood donors submitted at the Veterinary Teaching Hospitals of the Universities of Teramo (Abruzzo Region, Teramo, Italy) and Perugia (Umbria Region, Teramo, Italy), and visited at veterinary practitioners in Rome (Lazio Region, Teramo, Italy) using commercial immunochromatographic cartridges and commercial agglutination cards. There were four hundred and eighty-three cats included in the study. The frequencies of the blood types were: 89.9% type A, 7.0% type B, and 3.1% type AB. The probability of an acute hemolytic transfusion reaction or a neonatal isoerythrolysis was 6.5%. Although the frequency of type B in non-pedigree domestic cats living in Central Italy was relatively low, to reduce the risk of fatal transfusion reactions, blood group typing is recommended before each transfusion.
由于AB血型系统中存在天然同种抗体，输血反应和新生仔猫溶血病在猫科动物中很常见。已知猫血型的频率因地理区域和品种而异。因此，本研究的目的是调查意大利中部非纯种家猫的AB血型频率，并分别估计由输血不匹配或随机交配不相容引起的危及生命的输血反应和新生仔猫溶血病的风险。使用商业免疫层析试剂盒和商业凝集卡，对提交至特拉莫大学（意大利阿布鲁佐大区特拉莫）和佩鲁贾大学（意大利翁布里亚大区特拉莫）兽医教学医院的非纯种家猫患者和潜在献血者进行AB血型测定，并对罗马（意大利拉齐奥大区特拉莫）的兽医从业者处就诊的猫进行测定。本研究共纳入483只猫。血型频率为：A型89.9%，B型7.0%，AB型3.1%。急性溶血性输血反应或新生仔猫溶血病的概率为6.5%。尽管生活在意大利中部的非纯种家猫中B型的频率相对较低，但为降低致命输血反应的风险，建议每次输血前进行血型鉴定。
