巴基斯坦卡拉奇不孕不育中心就诊患者的抑郁和韧性与生育生活质量的关系。
Association of depression and resilience with fertility quality of life among patients presenting to the infertility centre for treatment in Karachi, Pakistan.
机构信息
School of Nursing and Midwifery, Aga Khan University, Karachi, Pakistan.
Department of Surgery, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
出版信息
BMC Public Health. 2020 Oct 23;20(1):1607. doi: 10.1186/s12889-020-09706-1.
BACKGROUND
In Pakistan there is a dire need to explore the quality of life in infertile males and females and its undesirable psychological outcomes. This, study aimed to compare the quality of life (QoL) of males and females visiting an infertility centre for treatment and to assess its association with resilience, depression, and other socio-demographic factors.
METHODS
An Analytical Cross-Sectional study was conducted amongst infertile males and females at the Australian Concept Infertility Medical Centre (ACIMC), Karachi, Pakistan. The non-probability (purposive) sampling strategy was used to recruit the participants. The sample size was 668. Data was analysed using STATA version 12. FertiQoL tool, Beck II Depression Inventory Tool and Resilience Scale 14 (RS-14) were used for assessing the quality of life, depression and resilience respectively of infertile patients.
RESULTS
Total 668 infertile patients, 334 males and 334 females participated in the study. The mean age was 35.53 ± 6.72, among males, and 30.87 ± 6.12 among females. The mean resilience scores were significantly higher among males, (77.64 ± 8.56), as compared to females (76.19 ± 8.69) (95% CI; - 2.757, - 0.1347). However, a significantly higher proportion of females were depressed (13.8%) as compared to males (6%). The mean QoL scores for the general health domain, emotional domain, mind and body domain, and relational domain, and the total QoL were significantly higher in males as compared to females (p value< 0.001); however, QoL for the social domain was not significantly different in both the groups. On multivariable linear regression resilience and depression among males had a significant association with QoL, after adjusting for the covariates educational status, monthly income, and number of friends. Similar association was observed among females after adjusting for the covariate monthly income only.
CONCLUSION
Fertility related QoL of men and women has a significant association with no formal education, number of friends, income, depression and resilience. Therefore, health care professionals in the field of infertility must be adequately trained to respond to the needs of individuals going through these psychological problems.
背景
在巴基斯坦，有必要探索不育男性和女性的生活质量及其不良心理后果。本研究旨在比较到不孕不育中心接受治疗的男性和女性的生活质量（QoL），并评估其与韧性、抑郁和其他社会人口因素的关系。
方法
在巴基斯坦卡拉奇的澳大利亚概念不孕不育医学中心（ACIMC），对不育男性和女性进行了一项分析性横断面研究。采用非概率（目的）抽样策略招募参与者。样本量为 668。使用 STATA 版本 12 分析数据。FertiQoL 工具、贝克 II 抑郁量表和韧性量表 14（RS-14）分别用于评估不孕患者的生活质量、抑郁和韧性。
结果
共有 668 名不孕患者，334 名男性和 334 名女性参加了研究。男性的平均年龄为 35.53±6.72 岁，女性为 30.87±6.12 岁。男性的平均韧性评分显著较高，为 77.64±8.56，而女性为 76.19±8.69（95%CI；-2.757，-0.1347）。然而，女性抑郁的比例明显更高（13.8%），而男性为 6%。男性一般健康领域、情绪领域、身心领域和关系领域的 QoL 评分以及总 QoL 评分均显著高于女性（p 值<0.001）；然而，两组的社会领域 QoL 评分没有显著差异。在多变量线性回归中，调整教育程度、月收入和朋友数量等协变量后，男性的韧性和抑郁与 QoL 显著相关。在仅调整月收入协变量后，也观察到女性存在类似的关联。
结论
男性和女性的生育相关 QoL 与无正规教育、朋友数量、收入、抑郁和韧性显著相关。因此，不孕不育领域的医疗保健专业人员必须接受充分培训，以满足正在经历这些心理问题的个人的需求。
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