Department of Social Medicine, School of Public Health, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, China.
English Department, School of Fundamental Sciences, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, China.
Health Qual Life Outcomes. 2019 Feb 15;17(1):38. doi: 10.1186/s12955-019-1099-8.
Infertility-related stress can seriously impact the fertility quality of life (QoL) of infertile women. Resilience, as a coping resource, can effectively combat psychological stress. This study aimed to evaluate the fertility QoL of infertile women and to examine whether resilience moderates the association of infertility-related stress with fertility QoL.
This cross-sectional study was conducted in northeast of China from December 2017 to February 2018. Out of 559 women outpatients with infertility, 498 (89.1%) completed self-reported questionnaires including the FertiQoL Scale, Fertility Problem Inventory (FPI) and Connor-Davidson Resilience Scale (CD-RISC). Hierarchical multiple regression analysis and simple slope analysis were applied to explore the influencing factors related to fertility QoL as well as to examine the moderating effect of resilience on the association of infertility-related stress with fertility QoL.
The mean FertiQoL score was 64.54 ± 16.90 among the participants. Household monthly income and causes of infertility were significantly related to fertility QoL. In addition, infertility-related stress was negatively related to fertility QoL, and resilience was positively associated with fertility QoL, explaining 36.3% of the variance. Resilience moderated the association of infertility-related stress with fertility QoL. Specifically, the effect of infertility-related stress on fertility QoL varied by low(1 SD below the mean, B = - 0.496, β = - 0.714, P < 0.001), mean (B = - 0.293, β = - 0.422, P < 0.001) and high (1 SD above the mean, B = - 0.090, β = - 0.130, P < 0.001) levels of resilience. The higher resilience was, the weaker the effect of infertility-related stress on fertility QoL was.
Overall, women with infertility in China had relatively low FertiQoL scores. Resilience influenced the association of infertility-related stress with fertility QoL. Infertile patients' psychological status must be addressed and adequate resilience-based interventions such as mindfulness-based skills should be provided to improve fertility QoL of women with infertility.
不孕相关的压力会严重影响不孕女性的生育生活质量（QoL）。韧性作为一种应对资源，可以有效地应对心理压力。本研究旨在评估不孕女性的生育 QoL，并探讨韧性是否调节了不孕相关压力与生育 QoL 的关系。
这是一项在中国东北地区进行的横断面研究，时间为 2017 年 12 月至 2018 年 2 月。在 559 名不孕女性门诊患者中，有 498 名（89.1%）完成了自我报告问卷，包括生育质量量表、生育问题量表（FPI）和康纳-戴维森韧性量表（CD-RISC）。采用分层多元回归分析和简单斜率分析来探讨与生育 QoL 相关的影响因素，并检验韧性对不孕相关压力与生育 QoL 关系的调节作用。
参与者的平均生育质量量表得分为 64.54±16.90。家庭月收入和不孕原因与生育质量相关。此外，不孕相关压力与生育质量呈负相关，而韧性与生育质量呈正相关，解释了 36.3%的方差。韧性调节了不孕相关压力与生育质量的关系。具体来说，不孕相关压力对生育质量的影响因韧性的低（低于平均值 1 个标准差，B=-0.496，β=-0.714，P<0.001）、中（B=-0.293，β=-0.422，P<0.001）和高（高于平均值 1 个标准差，B=-0.090，β=-0.130，P<0.001）水平而有所不同。韧性越高，不孕相关压力对生育质量的影响越弱。
总体而言，中国不孕女性的生育质量量表得分相对较低。韧性影响了不孕相关压力与生育质量的关系。必须关注不孕患者的心理状况，并提供基于正念的技能等充分的韧性干预措施，以提高不孕女性的生育质量。
