Suppr超能文献

初诊于肺病专家的哮喘患者的“能做”与“做了”。

"Can Do" Versus "Do Do" in Patients with Asthma at First Referral to a Pulmonologist.

机构信息

Basalt Rehabilitation Centre, Leiden, The Netherlands; Department of Pulmonary Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

Department of Research and Development, CIRO, Horn, The Netherlands; Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+) NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, The Netherlands; REVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium.

出版信息

J Allergy Clin Immunol Pract. 2021 Mar;9(3):1278-1284. doi: 10.1016/j.jaip.2020.09.049. Epub 2020 Oct 21.

Abstract

BACKGROUND

Pharmacotherapy is key in asthma control, including preventing lung function decline, in primary care. However, patients' physical functioning (eg, physical capacity [PC] [=can do] and physical activity [PA] [=do do]) correlates poorly with lung function. Therefore, a better insight into the physical function of patients with asthma is needed, using the "can do, do do" concept.

OBJECTIVE

To explore the "can do, do do" concept in adult patients with asthma at referral for the first time to an outpatient consultation of a pulmonologist.

METHODS

PC was measured using the six-minute walk test and PA by using an accelerometer. Patients were classified into quadrants: low PC (6-minute walking distance <70% predicted), low PA (<7000 steps/d, "'can't do, don't do"); preserved PC, low PA ("can do, don't do"); low PC, preserved PA ("'can't do, do do"); or preserved PC, preserved PA ("can do, do do").

RESULTS

A total of 479 patients with asthma had a median (interquartile range) 6-minute walking distance of 74% (66%-82%) predicted, and walked 6829 (4593-9075) steps/d. Only 29% were classified as "can do, do do," whereas 30% were classified as "can't do, don't do." The Asthma Control Questionnaire and the Asthma Quality of Life Questionnaire scores were worst in the "can't do" groups.

CONCLUSIONS

Low PC and/or PA was found in most patients with asthma at the index referral to a pulmonologist. An impaired PC is accompanied by a significantly reduced asthma control and disease-specific quality of life. This justifies further studies on safety and efficacy of nonpharmacological interventions, such as physiotherapy.

摘要

背景

药物治疗是控制哮喘的关键,包括预防肺功能下降,在初级保健中。然而,患者的身体机能(例如,身体能力[PC] [=能够]和身体活动[PA] [=做])与肺功能相关性差。因此,需要使用“能够,做”的概念,更深入地了解哮喘患者的身体功能。

目的

探讨首次转诊至肺科医生门诊的成年哮喘患者的“能够,做”概念。

方法

使用六分钟步行试验测量 PC,使用加速度计测量 PA。患者被分为四个象限:低 PC(6 分钟步行距离<70%预测值),低 PA(<7000 步/天,“不能做,不做”);保留 PC,低 PA(“能够,不做”);低 PC,保留 PA(“不能做,做”);或保留 PC,保留 PA(“能够,做”)。

结果

共有 479 例哮喘患者 6 分钟步行距离中位数(四分位间距)为 74%(66%-82%预测值),行走 6829(4593-9075)步/天。只有 29%被归类为“能够,做”,而 30%被归类为“不能做,不做”。哮喘控制问卷和哮喘生活质量问卷评分在“不能”组中最差。

结论

在索引转诊至肺科医生时,大多数哮喘患者存在低 PC 和/或 PA。PC 受损伴随着哮喘控制和疾病特异性生活质量显著降低。这证明了非药物干预(如物理治疗)的安全性和疗效的进一步研究是合理的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验