Pharmacy practice research unit, CHU Sainte-Justine, Montreal, QC, Canada.
Faculté de pharmacie, Université de Montréal, Montreal, QC, Canada.
Eur J Hosp Pharm. 2020 Nov;27(6):361-366. doi: 10.1136/ejhpharm-2018-001775. Epub 2019 Feb 22.
The objectives of this study were to review economic data on the use of closed system drug transfer devices (CSTDs) for preparing and administering hazardous drugs, and to evaluate the quality of data reporting as defined by the Consolidated Health Economic Evaluation Reporting Standards (CHEERS).
All references from a recent Cochrane review about CSTDs were evaluated for inclusion. A literature review was also conducted. Articles containing economic data about the use of CSTDs were retained for analysis. Two researchers independently graded the articles according to the 24-item CHEERS checklist.
Of the 138 articles identified initially, 12 were retained for analysis. Nine of these studies did not report acquisition costs or did not detail acquisition costs. Six studies reported economic benefits associated with the used of CSTDs, all related to extending the beyond-use date. The mean number of CHEERS criteria fulfilled by the included articles was 9.2 (SD 2.4).
CSTDs are costly to acquire. However, few studies have examined the economic impact of these devices, and the existing studies are incomplete. As a result, hospitals planning to implement these devices will be unable to make a sound economic evaluation. Robust economic evaluation of CSTDs is needed.
本研究旨在回顾用于准备和管理危害药物的密闭式药物传输装置（CSTD）的经济数据，并根据统一健康经济评估报告标准（CHEERS）评估数据报告的质量。
评估了最近一篇关于 CSTD 的 Cochrane 综述中的所有参考文献，以确定是否纳入。还进行了文献综述。保留了包含有关 CSTD 使用的经济数据的文章进行分析。两名研究人员根据 24 项 CHEERS 清单独立对文章进行评分。
最初确定的 138 篇文章中，有 12 篇被保留用于分析。其中 9 项研究未报告购置成本或未详细说明购置成本。6 项研究报告了使用 CSTD 的经济效益，均与延长有效期有关。纳入研究的 CHEERS 标准平均满足 9.2 项（SD 2.4）。
CSTD 的购置成本较高。然而，很少有研究检查这些设备的经济影响，而且现有研究并不完整。因此，计划实施这些设备的医院将无法进行合理的经济评估。需要对 CSTD 进行强有力的经济评估。
