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交互式编辑虚拟腱索以模拟决策支持系统中的二尖瓣。

Interactive editing of virtual chordae tendineae for the simulation of the mitral valve in a decision support system.

机构信息

Fraunhofer MEVIS, Bremen, Germany.

Charité-Universitätsmedizin Berlin, Berlin, Germany.

出版信息

Int J Comput Assist Radiol Surg. 2021 Jan;16(1):125-132. doi: 10.1007/s11548-020-02230-y. Epub 2020 Oct 24.

Abstract

PURPOSE

Decision support systems for mitral valve disease are an important step toward personalized surgery planning. A simulation of the mitral valve apparatus is required for decision support. Building a model of the chordae tendineae is an essential component of a mitral valve simulation. Due to image quality and artifacts, the chordae tendineae cannot be reliably detected in medical imaging.

METHODS

Using the position-based dynamics framework, we are able to realistically simulate the opening and closing of the mitral valve. Here, we present a heuristic method for building an initial chordae model needed for a successful simulation. In addition to the heuristic, we present an interactive editor to refine the chordae model and to further improve pathology reproduction as well as geometric approximation of the closed valve.

RESULTS

For evaluation, five mitral valves were reconstructed based on image sequences of patients scheduled for mitral valve surgery. We evaluated the approximation of the closed valves using either just the heuristic chordae model or a manually refined model. Using the manually refined models, prolapse was correctly reproduced in four of the five cases compared to two of the five cases when using the heuristic. In addition, using the editor improved the approximation in four cases.

CONCLUSIONS

Our approach is suitable to create realistically parameterized mitral valve apparatus reconstructions for the simulation of normally and abnormally closing valves in a decision support system.

摘要

目的

二尖瓣疾病的决策支持系统是个性化手术规划的重要一步。决策支持需要模拟二尖瓣装置。构建二尖瓣模拟的腱索模型是其重要组成部分。由于图像质量和伪影的原因,腱索在医学成像中无法可靠地检测到。

方法

我们使用基于位置的动力学框架,能够逼真地模拟二尖瓣的开闭。在这里,我们提出了一种启发式方法,用于构建成功模拟所需的初始腱索模型。除了启发式方法,我们还提供了一个交互编辑器,用于细化腱索模型,并进一步改善病理学再现以及关闭瓣膜的几何逼近。

结果

为了评估,根据计划接受二尖瓣手术的患者的图像序列,重建了五个二尖瓣。我们使用仅启发式腱索模型或手动细化模型评估关闭瓣膜的逼近程度。与使用启发式方法的五个病例中的两个相比,使用手动细化模型,在四个病例中正确再现了脱垂。此外,使用编辑器在四个病例中改善了逼近程度。

结论

我们的方法适用于创建真实参数化的二尖瓣装置重建,以模拟决策支持系统中正常和异常关闭的瓣膜。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dcd/7822807/24b048cf2b25/11548_2020_2230_Fig1_HTML.jpg

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