Devonec M
Unité de Néphro-Urologie, INSERM, CNRS UA 1177, Hôpital E. Herriot, Lyon, France.
Prog Clin Biol Res. 1987;243B:1-10.
The high frequency endocavitary sectorial probe developed by the authors has been used for the evaluation of transrectal ultrasonography as a diagnostic method for prostatic cancer. A double-blind study was conducted with retrospective interpretation of the ultrasonographic documents obtained from a series of 213 patients. Histological control was available in 132 patients, including 42 patients with cancer. The specificity for the diagnosis of cancer (number of true negatives/number of patients without cancer) was 79%, while the sensitivity (number of true positives/number of cancers) was only 48%. In the second phase of the study, ultrasound guided prostatic needle biopsy was performed in a series of 72 patients with either prostatic induration without a nodule (47 cases) or with a prostatic nodule (25 cases). The histological material was of good quality and no complications were recorded. However, the ten cancers diagnosed (5 from each group) could not be clearly distinguished ultrasonographically from other examinations of adenoma, prostatitis or normal prostate.
作者研发的高频腔内扇形探头已用于经直肠超声检查评估，作为前列腺癌的一种诊断方法。对从213例患者系列中获得的超声文档进行回顾性解读，开展了一项双盲研究。132例患者有组织学对照，其中42例患有癌症。癌症诊断的特异性（真阴性数/无癌症患者数）为79%，而敏感性（真阳性数/癌症数）仅为48%。在研究的第二阶段，对一系列72例患者进行了超声引导下前列腺穿刺活检，这些患者要么有前列腺硬结但无结节（47例），要么有前列腺结节（25例）。组织学材料质量良好，未记录到并发症。然而，所诊断出的10例癌症（每组5例）在超声检查中无法与腺瘤、前列腺炎或正常前列腺的其他检查结果清楚区分开来。
