Devonec M, Codas H, Provensal B, Chapelon J Y, Dubernard J M, Cathignol D
Ann Urol (Paris). 1987;21(1):17-22.
Endorectal ultrasonography was evaluated in the diagnosis of prostatic cancer, using a high frequency (7,5 MHz) mechanical sectorial endocavitary probe developed by the authors. In a first study, sonograms from a series of 213 patients were interpreted retrospectively without any knowledge of the clinical or pathological findings. Specificity for the diagnosis of cancer (true non-malignant/total non-malignant) reached 79%, whereas sensitivity (true malignant/total malignant) was only 48%. Pathology was available for 132 patients. In a second study, 72 ultrasonically guided biopsies were performed in patients presenting either with a suspicious induration without nodule (47 cases) or a palpable nodule (25 cases). Good quality biopsy specimens, and absence of complication were remarkable. However, the 10 cancer cases (5 diagnosed in each group) did not show sonographically clearly different from the remaining adenoma, prostatitis and normal cases.
使用作者开发的高频(7.5兆赫)机械扇形腔内探头,对直肠内超声检查在前列腺癌诊断中的应用进行了评估。在第一项研究中,对213例患者的超声图像进行回顾性解读,事先不了解临床或病理检查结果。癌症诊断的特异性(真阴性/总阴性)达到79%,而敏感性(真阳性/总阳性)仅为48%。132例患者有病理检查结果。在第二项研究中,对72例患者进行了超声引导下活检,这些患者要么表现为无可触及结节的可疑硬结(47例),要么表现为可触及结节(25例)。高质量的活检标本以及无并发症情况显著。然而,10例癌症病例(每组各诊断出5例)在超声图像上与其余的腺瘤、前列腺炎和正常病例并无明显差异。