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探索新冠疫情新常态下的未知领域。

Exploring the unknown territories in the new normal world of COVID.

作者信息

Bajwa Sukhminder Jit Singh, Gupta Ritu, Wahi Ajay, Goraya S P S

机构信息

Department of Anaesthesiology and Intensive Care, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab, India.

Department of Obstetrics and Gynaecology, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab, India.

出版信息

J Anaesthesiol Clin Pharmacol. 2020 Aug;36(Suppl 1):S77-S80. doi: 10.4103/joacp.JOACP_350_20. Epub 2020 Jul 25.

DOI:10.4103/joacp.JOACP_350_20
PMID:33100651
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7573994/
Abstract

It is now well known that the severe acute respiratory syndrome (SARS-CoV-2) originated in the Wuhan province of Hubei, China in 2019. Having spread across different countries of the world, this highly contagious disease has posed many challenges for the healthcare workers to work without endangering themselves and their patients' wellbeing. Several things are yet not clear about the virus and the presence or absence of the virus in the cerebrospinal fluid (CSF) is currently a debated topic. This article reports the perioperative management of two coronavirus disease-19 positive cases, one of whom was a pregnant patient. Their CSF samples, which were collected during the administration of spinal anesthesia, tested to be negative for viral reverse transcription polymerase chain reaction (RT-PCR) test. We wish to highlight from these cases, that during spinal anesthesia, CSF in mildly symptomatic COVID-19 cases probably does not pose a risk of transmission to the anesthesiologist. However, we suggest that due to the varied presentations of the virus, health care personnel, especially anesthesiologists have to be careful during the perioperative management of such cases.

摘要

众所周知,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)于2019年起源于中国湖北省武汉市。这种高传染性疾病已蔓延至世界各国,给医护人员在不危及自身及患者健康的情况下开展工作带来了诸多挑战。关于该病毒仍有一些情况尚不清楚,其在脑脊液(CSF)中是否存在目前仍是一个有争议的话题。本文报道了两例新型冠状病毒肺炎阳性病例的围手术期管理情况,其中一例为孕妇。她们在脊髓麻醉给药期间采集的脑脊液样本,经病毒逆转录聚合酶链反应(RT-PCR)检测呈阴性。我们希望从这些病例中强调,在脊髓麻醉期间,症状较轻的新型冠状病毒肺炎病例的脑脊液可能不会对麻醉医生构成传播风险。然而,我们建议,由于该病毒表现多样,医护人员,尤其是麻醉医生在对此类病例进行围手术期管理时必须谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aca/7573994/adc2efb67894/JOACP-36-77-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aca/7573994/adc2efb67894/JOACP-36-77-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aca/7573994/adc2efb67894/JOACP-36-77-g001.jpg

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本文引用的文献

1
Anaesthetic management of a COVID-19 parturient for caesarean section - Case report and lessons learnt.一名新冠病毒病产妇剖宫产的麻醉管理——病例报告及经验教训
Indian J Anaesth. 2020 May;64(Suppl 2):S141-S143. doi: 10.4103/ija.IJA_509_20. Epub 2020 May 23.
2
COVID Operation Theatre- Advisory and Position Statement of Indian Society of Anaesthesiologists (ISA National).新冠手术室——印度麻醉医师协会(印度麻醉医师协会全国委员会)的咨询意见与立场声明
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3
[Anesthesia management in cesarean section for patient with COVID-19: a case report].
新型冠状病毒肺炎患者脑脊液特征的系统评价研究。
J Neurol Sci. 2021 Feb 15;421:117316. doi: 10.1016/j.jns.2021.117316. Epub 2021 Jan 10.
[新型冠状病毒肺炎患者剖宫产手术的麻醉管理:一例病例报告]
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020 May 25;49(2):249-252. doi: 10.3785/j.issn.1008-9292.2020.03.04.
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Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke.COVID-19 患者和卒中患者脑脊液中 SARS-CoV-2 的状况。
J Neurol Neurosurg Psychiatry. 2020 Aug;91(8):846-848. doi: 10.1136/jnnp-2020-323522. Epub 2020 Apr 30.
5
Neurological Complications of Coronavirus Disease (COVID-19): Encephalopathy.冠状病毒病(COVID-19)的神经系统并发症:脑病
Cureus. 2020 Mar 21;12(3):e7352. doi: 10.7759/cureus.7352.
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A first case of meningitis/encephalitis associated with SARS-Coronavirus-2.首例与 SARS-CoV-2 相关的脑膜炎/脑炎。
Int J Infect Dis. 2020 May;94:55-58. doi: 10.1016/j.ijid.2020.03.062. Epub 2020 Apr 3.
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Nervous system involvement after infection with COVID-19 and other coronaviruses.感染 COVID-19 和其他冠状病毒后的神经系统并发症。
Brain Behav Immun. 2020 Jul;87:18-22. doi: 10.1016/j.bbi.2020.03.031. Epub 2020 Mar 30.
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Spinal anaesthesia for patients with coronavirus disease 2019 and possible transmission rates in anaesthetists: retrospective, single-centre, observational cohort study.新冠病毒 2019 患者的脊髓麻醉和麻醉师的可能传播率:回顾性、单中心、观察性队列研究。
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